Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Author "Gachanja, J"

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Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva

Graham, SP; Pellé, R; Yamage, M; Mwangi, DM; Honda, Y; Mwakubambanya, RS; de Villiers, EP; Abuya, E; Awino, E; Gachanja, J; Mbwika, F; Muthiani, AM; Muriuki, C; Nyanjui, JK; Onono, FO; Osaso, J; Riitho, V; Saya, RM; Ellis, SA; McKeever, DJ; MacHugh, ND; Gilbert, SC; Audonnet, JC; Morrison, WI; van der, Bruggen P; Taracha, EL (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2008-02)

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility ...
Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

Mwangi, DM; Honda, Y; Graham, SP; Pelle, R; Taracha, EL; Gachanja, J; Nyanjui, JK; Bray, J; Palmern, GH; Brown, WC; Mwagi, W (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2011-04)

Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing ...