Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Author "Yu, Longzheng"
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Cloning, characterization and validation of inosine 5′-monophosphate
Cao, Shinuo; Aboge, Gabriel Oluga; Terkawi, Mohamad Alaa; Zhou, Mo; Yu, Longzheng; Luo, Yuzi; Li, Yan; Goo, Younkyoung; Kamyingkird, Ketsarin; Masatani, Tatsunori; Suzuk, Hiroshi; Igarashi, Ikuo; Yoshifumi Nishikawa; Xuenan Xuan (Department of Public Health Pharmacology and Toxicology, 2013) -
Cloning, characterization and validation of inosine 5′-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target
Xuan, Xuenan; Nishikawa, Yoshifumi; Igarashi, Ikuo; Suzuki, Hiroshi; Masatani, Tatsunori; Kamyingkird, Ketsarin; Goo, Younkyoung; Li, Yan; Yu, Longzheng; Luo, Yuzi; Zhou, Mo; Terkawi, Mohamad A; Aboge, Gabriel O; Cao, Shinuo (Department of Public Health, Pharmacology and Toxicology, 2013-04)The inosine monophosphate dehydrogenase (IMPDH) enzyme has been characterized and validated as a molecular drug target in other apicomplexans but not in the genus Babesia. Subsequently, we cloned and expressed a Babesia ... -
Expression of truncated Babesia gibsoni thrombospondin-related adhesive proteins in Escherichia coli and evaluation of their diagnostic potential by enzyme-linked immunosorbent assay
Narantsatsral, S; Goo, Youn-Kyoung; Battsetseg, B; Myagmarsuren, P; Terkawi, Mohamad Alaa; Soma, Takehisa; Luo, Yuzi; Lia, Yan; Cao, Shinuo; Yu, Longzheng; Kamyingkird, Ketsarin; Aboge, Gabriel Oluga; Nishikawa, Yoshifumi; Xuan, Xuenan (2011)Among the previously established enzyme-linked immunosorbent assays (ELISAs), an ELISA using the full length of a recombinant thrombospondin-related adhesive protein of Babesia gibsoni (rBgTRAPf) is considered as the most ... -
Macrophages Are Critical for Cross-Protective Immunity Conferred by Babesia microti against Babesia rodhaini Infection in Mice
Li, Yan; Terkawi, Mohamad Alaa; Nishikawa, Yoshifumi; Aboge, Gabriel Oluga; Luo, Yuzi; Ooka, Hideo; Goo, Youn-Kyoung; Yu, Longzheng; Cao, Shinuo; Sun, Yongfeng; Yamagishi, Junya; Masatani, Tatsunori; Yokoyama, Naoaki; Igarashi, Ikuo; Xuan, Xuenan (Department of Public Health, Pharmacology and Toxicology, 2012)AlthoughprimaryinfectionofmicewithBabesiamicrotihasbeenshowntoprotectmiceagainstsubsequentlethalinfection by Babesiarodhaini,themechanismbehindthecross-protection is unknown.To unravel lthis mechanism,we investigated the ... -
Molecular detection and identification of Babesia bovis and Babesia bigemina in cattle in northern Thailand
Cao, Shinuo; Aboge, Gabriel Oluga; Terkawi, Mohamad Alaa; Yu, Longzheng; Kamyingkird, Ketsarin; Luo, Yuzi; Li, Yan; Goo, Youn-Kyoung; Yamagishi, Junya; Nishikawa, Yoshifumi; Yokoyama, Naoaki; Suzuki, Hiroshi; Igarashi, Ikuo; Maeda, Ryuichiro; Inpankaew, Tawin; Jittapalapong, Sathaporn; Xuan, Xuenan (2012)Although Babesia bovis and Babesia bigemina infections cause economic losses in the cattle industry in northern Thailand, there is inadequate information on Babesia isolates present in the area. Therefore, to determine the ... -
Protective effect of a prime-boost strategy with plasmid DNA followed by recombinant adenovirus expressing TgAMA1 as vaccines against Toxoplasma gondii infection in mice
Yu, Longzheng; Yamagishi, Junya; Zhang, Shoufa; Jin, Chunmei; Aboge, Gabriel Oluga; Zhang, Houshuang; Zhang, Guohong; Tanaka, Tetsuya; Fujisaki, Kozo; Nishikawa, Yoshifumi; Xuan, Xuenan (2012)A heterologous prime-boost strategy with priming plasmid DNA followed by recombinant virus expressing relevant antigens is known to stimulate protective immunity against intracellular parasites. In this study, we have ...