Browsing Faculty of Science & Technology (FST) by Author "Irungu, Beatrice N"

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    • Antiplasmodial and cytotoxic activities of the constituents of turraea robusta and turraea nilotica 

      Irungu, Beatrice N; Adipoa, Nicholas; Orwa, Jennifer A.; Kimanic, Francis; Heydenreich, Matthias; Midiwoe, Jacob O; Björemark, Per Martin; Håkanssonb, Mikael; Yenesew, Abiy; Erdélyi, Máté (University of Nairobi, 2015-08)
      Ethnopharmacological relevance Turraea robusta and Turraea nilotica are African medicinal plants used for the treatment of a wide variety of diseases, including malaria. The genus Turraea is rich in limonoids and other ...

    • The antiplasmodial and radical scavenging activities of flavonoids of Erythrina burttii 

      Yenesew, Abiy; Akala, Hoseah M; Twinomuhwezi, Hannington; Chepkirui, Carolyne; Irungu, Beatrice N; Eyase, Fredrick L; Kamatenesi-Mugisha, Maud; Kiremire, Bernard T; Johnson, Jacob D; Waters, Norman C (Department of Chemistry, University of NairobiUnited States Army Medical Research Unit-Kenya, Walter Reed Project, USASchool of Bio-Sciences, College of Natural Sciences, Makerere University, UgandaDepartment of Chemistry, Makerere University, UgandaCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute (KEMRI)Department of Chemistry and Life Science, United States Military Academy, USA, 2012-08)
      The acetone extract of the root bark of Erythrina burttii showed in vitro antiplasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values of ...

    • Constituents of the Roots and Leaves of Ekebergia capensis and Their Potential Antiplasmodial and Cytotoxic Activities 

      Yenesew, Abiy; Erdélyi, Máté; Midiwo, Jacob; Kimani, Francis; Landberg, Göran; Fitzpatrick, Paul A; Gruhonjic, Amra; Orwa, Jennifer A; Irungu, Beatrice N (2014)
      A new triterpenoid, 3-oxo-12β-hydroxy-oleanan-28,13β-olide (1), and six known triterpenoids 2–7 were isolated from the root bark of Ekebergia capensis, an African medicinal plant. A limonoid 8 and two glycoflavonoids 9–10 ...