Browsing Faculty of Science & Technology (FST) by Author "Nchiozem-Ngnitedem, Vaderament-A"
Now showing items 1-11 of 11
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Anti-inflammatory norhopanes from the root bark of Fagaropsis angolensis (Engl.) H.M.Gardner
Mukavi, Justus; Omosa, Leonidah K; Nchiozem-Ngnitedem, Vaderament-A; Nyaga, Justin; Omole, Ruth; Gabin, Thierry M B; Michael, Spiteller (University of Nairobi, 2020)Two new norhopane derivatives namely 3β,6β,22-trihydroxy-7β,11α-di[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (1) and 3β,6β,22-trihydroxy-7β-[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (2) together with two ... -
Antibacterial Activities of Thirteen Naturally Occuring Compounds From Two Kenyan Medicinal Plants: Zanthoxylum Paracanthum (Mildbr) Kokwaro (Rutaceae) and Dracaena Usambarensis Engl. (Asparagaceae) Against MDR Phenotypes
Omosa, Leonidah K; Nchiozem-Ngnitedem, Vaderament-A; Guefack, Michel-Gael F; Mbaveng, Armelle T; Kuete, Victor (University of Nairobi, 2022)The antibacterial potency of thirteen compounds reported from two distinct genera, Zanthoxylum (Rutaceae) and Dracaena (Asparagaceae) against a panel of sensitive and multi-drug resistant Gram-positive and Gram-negative ... -
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
Jepkoech, Clara; Omosa, Leonidah K; Nchiozem-Ngnitedem, Vaderament-A; Kenanda, Evans O; Guefack, Michel-Gael F; Mbaveng, Armelle T; Kuete, Victor; Heydenreich, Matthias (University of Nairobi, 2022)Purification of the aerial parts of Vernonia auriculifera Hiern afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6). Their structures were determined using spectral evidences as well as by comparison with ... -
Antiplasmodial and Antimicrobial Activities of Ent- Abietane Diterpenoids From the Roots of Suregada Zanzibariensis
Midiwo, Jacob O; Yenesew, Abiy; Omosa, Leonidah K.; Matundura, Jackson O; Kumarihamy, Mallika; Zhao, Jianping; Wang, Mei; Tripathi, Siddharth; Khan, Shabana; Masila, Veronica M; Nchiozem-Ngnitedem, Vaderament-A; Muhammad, Ilias (University of Nairobi, 2022)The root extract ofSuregada zanzibariensisBaill. afforded six previ-ously describedent-abietane diterpenoids, namely 7-oxo-ent-abieta-5(6),8(14),13(15)-trien-16,12-olide (1), mangiolide (2),8,14b:11,12a-diepoxy ... -
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
Omosa, Leonidah K; Nchiozem-Ngnitedem, Vaderament-A; Mukavi, Justus; Okoko, Brenda A; Nyaboke, Helder O; Ibrahim, Hashim; Matundura, Jackson O; Efferth, Thomas; Spiteller, Michael (University of Nairobi, 2022)Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ... -
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
Nchiozem-Ngnitedem, Vaderament-A; Omosa, Leonidah K; Derese, Solomon; Efferth, Thomas; Spiteller, Michael (University of Nairobi, 2022)Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy c ... -
Flavanols from Tetrapleura tetraptera with cytotoxic activities
Ayoolu, Oguntimehin S; Ogbole, Omonike O; Ajaiyeoba, Edith O; Nchiozem-Ngnitedem, Vaderament-A; Demissie, Taye B; Elbadawi, Mohamed; Efferth, Thomas; Bedane, Kibrom G; Spitelle, Michael (University of Nairobi, 2022-05)Tetrapleura tetraptera is a medicinal plant used in East and West Africa to treat inflammation and related diseases. From the stem bark of the plant, three previously undescribed flavan-3-ol derivatives named (2R,3S)-3,3 ... -
Inhibition of Proinflammatory Cytokine Release by Flavones and Flavanones from the Leaves of Dracaena steudneri Engl
Nchiozem-Ngnitedem, Vaderament-A; Omosa, Leonidah K; Bedane, Kibrom G; Derese, Solomon; Michael, Spiteller (University of Nairobi, 2021-03)The leaves of Dracaena steudneri yielded 6 new flavonoids-3,5,7-trihydroxy-6-methyl-3',4'-methylenedioxyflavone (1: ), 5,7-dihydroxy-3-methoxy-6-methyl-3',4'-methylenedioxyflavone (2: ), 3,5,7-trihydroxy-6-methoxy-3',4'- ... -
Laboratory and Field Performance of Metarhizium Anisopliae Isolate Icipe 41 for Sustainable Control of the Invasive Fall Armyworm Spodoptera Frugiperda (Lepidoptera: Noctuidae)
Munywoki, Joseph; Omosa, Leonidah K; Subramanian, Sevgan; Mfuti, David K; Njeru, Ezekiel M; Nchiozem-Ngnitedem, Vaderament-A; Akutse, Komivi S (University of Nairobi, 2022)To overcome the negative impacts of invasive fall armyworm (FAW), this study assessed the laboratory and field efficacy of aqueous and oil-based formulations of Metarhizium anisopliae ICIPE 41 as an alternative source ... -
Mechanism of Action of Endophytic Fungi Hypocrea Lixii and Beauveria Bassiana in Phaseolus Vulgaris as Biopesticides Against Pea Leafminer and Fall Armyworm
Chebet, Olivia N; Omosa, Leonidah K; Subramanian, Sevgan; Nchiozem-Ngnitedem, Vaderament-A; Mmari, John O; Akutse, Komivi S (University of Nairobi, 2021-09)Endophytic fungal isolates Hypocrea lixii F3ST1 and Beauveria bassiana G1LU3 were evalu- ated for their potential to endophytically colonize and induce active compounds in Phaseolus vulgaris, as a defense mechanism against ... -
Potential Antibacterial Pharmaceuticals From the Flora of Africa
Mbaveng, Armelle T; Omosa, Leonidah K; Bitchagno, Gabin T.M; Kuete, Jenifer R.N; Nchiozem-Ngnitedem, Vaderament-A; Kuete, Victor (University of Nairobi, 2022)The present chapter highlights the antibacterial potential of nine highly active compounds isolated from the African medicinal plants: 8,8-bis-(dihydroconiferyl)- diferulate, buesgenine, candidone, diospyrone, ferruginin ...