Browsing Faculty of Science & Technology (FST) by Author "Ndakala, Albert"
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3-Oxo-14α,15α-epoxyschizozygine: A new schizozygane indoline alkaloid from Schizozygia coffaeoides
Atilaw, Yoseph; Heydenreich, Matthias; Ndakala, Albert (University of Nairobi, 2014-07)The stem bark extract of the Schizozygia coffaeoides (Apocynaceae) showed moderate antiplasmodial activity (IC50 = 8–12 μg/mL) against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium ... -
Antiplasmodial and antileishmanial flavonoids from Mundulea sericea
Chepkirui, Carolyne; Ochieng, Purity J; Sarkar, Biswajyoti; Hussain, Aabid; Pal, Chiranjib; Yang, Li Jun; Coghi, Paolo; Akala, Hoseah M; Derese, Solomon; Ndakala, Albert; Heydenreich, Matthias; Wong, Vincent K W; Erdélyi, Máté; Yenesew, Abiy (University of Nairobi, 2020)Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using ... -
Benzo[ b]naphtho[2,1- d]furans and 2-Phenylnaphthalenes from Streblus usambarensis
Chepkirui, Carolyne; Adem, Fozia Ali; Rudenko, Anastasia; Gütlin, Yukino; Ndakala, Albert; Derese, Solomon; Orthaber, Andreas; Bourgard, Catarina; Yenesew, Abiy; Erdélyi, Máté (University of Nairobi, 2023)Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated ... -
Benzo[ b]naphtho[2,1- d]furans and 2-Phenylnaphthalenes from Streblus usambarensis
Chepkirui, Carolyne; Adem, Fozia A; Rudenko, Anastasia; Gütlin, Yukino; Ndakala, Albert; Derese, Solomon; Orthaber, Andreas; Bourgard, Catarina; Yenesew, Abiy; Erdélyi, Máté (University of Nairobi, 2023)Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated ... -
Knipholone cyclooxanthrone and an anthraquinone dimer with antiplasmodial activities from the roots of Kniphofia foliosa
Abdissa, Negera; Indulia, Martha; Akala, Hoseah M; Heydenreich, Matthias; Midiwo, Jacob O; Ndakala, Albert; Yenesew, Abiy (Department of Chemistry, 2013)A new phenylanthrone, named knipholone cyclooxanthrone and a dimeric anthraquinone, 10-methoxy-10,7′-(chrysophanol anthrone)-chrysophanol were isolated from the roots of Kniphofia foliosa together with the rare naphthalene ... -
A new β-hydroxydihydrochalcone from Tephrosia uniflora, and the revision of three β-hydroxydihydrochalcones to flavanones
Chepkirui, Carolyne; Bourgard, Catarina; Gilissen, Pieter J; Ndakala, Albert; Derese, Solomon; Gütlin, Yukino; Erdélyi, Máté; Yenesew, Abiy (University of Nairobi, 2022-04)The CH2Cl2/MeOH (1:1) extract of the stems of Tephrosia uniflora yielded the new β-hydroxydihydrochalcone (S)-elatadihydrochalcone-2'-methyl ether (1) along with the three known compounds elongatin (2), (S)-elatadihydrochalcone ... -
Pentadihydronaphthoquinones A-D from the roots of Pentas bussei
Endale, Milkyas; Ekberg, Annabel; Akala, Hoseah M; Eyase, Fredrick L; Walsh, Douglas S; Mbugua, Martin; Ndakala, Albert; Alao, John P; Sunnerhagen, Per; Erdelyi, Mate; Yenesew, Abiy (University of Nairobi, 2012) -
Synergistic anti-inflammatory activities of a new flavone and other flavonoids from Tephrosia hildebrandtii vatke
Owor, Richard O; Gebreheiwot Bedane, Kibrom; Openda, Yolande I; Zühlke, Sebastian; Derese, Solomon; Ong'amo, George; Ndakala, Albert; Spiteller, Michael (University of Nairobi, 2020)A new flavone, named hildeflavone (1) along with 7 other known flavonoids were isolated from the aerial parts of Tephrosia hildebrandtii Vatke. Their characterisation was based on NMR and MS data analysis. The anti-inflammatory ...