Browsing Faculty of Science & Technology (FST) by Author "Tekwani, BL"

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    • Antileishmanial Activity of Kenyan Medicinal Plants 

      Muhammad, I; Midiwo, J; Tekwani, BL; Samoylenko, V; Sahu, R; Machumi, F; Rahman, AA; Walker, LA; Hester, JP (University of Nairobi, 2008)
      The EtOH extracts of two hundred thirteen medicinal plants, collected in various parts of Kenya, were tested for in vitro antileishmanial activity using Leishmania donovanii promastigotes. Thirty five plant extracts (i.e., ...

    • Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus. 

      Machumi, F; Yenesew, Abiy; Midiwo, JO; Heydenreich, M; Kleinpeter, E; Tekwani, BL; Khan, SI; Walker, LA; Muhammad, I (University of NairobiDepartment of Chemistry, 2012-09)
      The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...

    • Antiparasitic And Antimicrobial Constituents From Terminalia Brownii 

      Machumi, F; Zhang, J; Midiwo, JO; Jacob, MR; Khan, SI; Tekwani, BL; Walker, LA; Muhammad, I (University of Nairobi, 2013)
      Terminalia brownii is an African medicinal plant used to treat parasitic and microbial infections. A new oleanane-type triterenoid was isolated from its stem bark extract by bioassay-guided fractionation using the method ...

    • Phytochemical, Antiparasitic and Antimicrobial Investigations of Terminalia brownii 

      Machumi, F; Midiwo, JO; MR Jacob; Khan, SI; Tekwani, BL; Walker, LA; Muhammad, I (Department of Chemistry, University of Nairobi, 2013)
      Terminalia brownii is an African medicinal plant used to treat parasitic and microbial infections [1]. Chromatographic separations on the stem bark extract aimed at identifying the active components led to isolation of a ...