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Antiplasmodial Biflavanones from the Stem Bark of Garcinia buchananii Engl.

Omole, Ruth A; Moshi, Mainen J; Heydenreich, Matthias; Malebo, Hamisi M; Gathirwa, Jeremiah W; Oriko, Richard O; Omosa, Leonida Kerubo; Midiwo, Jacob Ogweno (University of Nairobi, 2019)

Introduction: Plants of the genus Garcinia are traditionally used treat a range of infectious and non-infectious diseases. Garcinia species are reported to have been shown to have a range of biological activities including ...

Two novel lignans derivatives and two fusicoccane diterpenoids from whole plant of Hypoestes verticillaris (L.f.) Sol. ex Roem. & Schult

Heydenreich, Matthias; Malebo, Hamisi M; Gathirwa, Jeremiah W; Omosa, Leonida K; Midiwo, Jacob O; Ochieng, Sharon Alice; Omole, Ruth A; Moshi, Mainen J (University of Nairobi, 2019)

Bioassay-guided screening of Hypoestes verticillaris whole plant CH2Cl2:MeOH (1:1) extract for anti-plasmodial activity yielded four new compounds: two lignans 2, 6-dimethoxysavinin (1), 2,6-dimethoxy-(7E)-7,8-dehydrohel ...