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Anti-leishmanial activity of some surface compounds of Tarchonanthus camphoratus
(University of Nairobi, 2019)
Background: The World Health Organization recognizes leishmaniasis as a major tropical disease with no effective vaccine against it.
Chemotherapy, the only effective way to treat all forms of the disease, is toxic and ...
Antiproliferative Properties of Labdane Diterpenoids from Croton sylvaticus Hochst against Drug Sensitive and Resistant Leukemia cell lines
(University of Nairobi, 2019)
Background: Cancer treatment failure is majorly attributed to the emergency of multi-drug resistance of cancer cells towards most conventional
drugs used in chemotherapy hence the need for more active principles with less ...
Oleanolic Acid and other Compounds Isolated from Cordia africana Lam which Inhibit Vancomycin Resistant Enterococcus
(University of Nairobi, 2019)
ABSTRACT
Introduction: Treatment of microbial infections has become complicated
due to increased resistance of microbes to the current drugs. The current
study investigates crude extracts and seven compounds from root ...
Rapid Screening using GIBEX Screens-to-nature System of Ethnomedicinal Plants from Ngong Forest, Kenya for Potency against Infectious Diseases and Antioxidant Activities: A Qualitative Study
(University of Nairobi, 2019)
Introduction: Plants from Kenyan flora are traditionally used to manage a number of ailments including; chronic and infectious disease, to bolster the body immunity and for general health protections. The current investigation ...
Antibacterial Activities and Phytochemical Screening of Crude Extracts from Kenyan Macaranga Species Towards MDR Phenotypes Expressing Effux Pumps
(University of Nairobi, 2021)
Macaranga species are traditionally used for the
treatment and management of coughing, fungal infection, and wounds.
In this study, the phytochemical screening and antibacterial activities
of nine crude extracts from ...
Mechanism of Action of Endophytic Fungi Hypocrea Lixii and Beauveria Bassiana in Phaseolus Vulgaris as Biopesticides Against Pea Leafminer and Fall Armyworm
(University of Nairobi, 2021-09)
Endophytic fungal isolates Hypocrea lixii F3ST1 and Beauveria bassiana G1LU3 were evalu-
ated for their potential to endophytically colonize and induce active compounds in Phaseolus vulgaris,
as a defense mechanism against ...
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
(University of Nairobi, 2022)
Purification of the aerial parts of Vernonia auriculifera Hiern
afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6).
Their structures were determined using spectral evidences as well
as by comparison with ...
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
(University of Nairobi, 2022)
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ...
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)
Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants
have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy
c ...
Laboratory and Field Performance of Metarhizium Anisopliae Isolate Icipe 41 for Sustainable Control of the Invasive Fall Armyworm Spodoptera Frugiperda (Lepidoptera: Noctuidae)
(University of Nairobi, 2022)
To overcome the negative impacts of invasive fall armyworm (FAW), this study assessed
the laboratory and field efficacy of aqueous and oil-based formulations of Metarhizium anisopliae
ICIPE 41 as an alternative source ...