Search
Now showing items 1-10 of 11
Anthraquinones of the roots of Pentas micrantha
(University of Nairobi, 2012-12)
Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 ...
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
(University of Nairobi, 2012-09)
The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...
Two new isoflavones from millettia dura
(2010)
The genus Millettia belongs to the family Fabaceae. It is
represented by more than 200 species and is, found widely
distributed in tropical Africa, Australia and Asia. Previous
chemical investigationsof a number" of ...
Natural Products from Plant Diversity and their Potential in Management of Neglected Diseases
(2011)
Conventionally, neglected diseases are considered as a group of 13 infectious diseases that are
. endemic in the low income populations in the tropical developing world. They can be classified
as those caused by trypanosomal ...
Friedelane triterpoids from rawsonia lucida
(2010)
Rawsonia lucida (Flacourtiaceae) is an evergreen tree or shrub
that is mainly distributed in tropical and southern Africa.
Recent survey of plants traditionally used for the treatment of
malaria have shown that the ...
Bioactivity of 'Flemingin A' and other Natural Products from the leaves of Flemingia grahamiana
(2011)
Flemingia graharriiana (Wight & Arn.) is an erect herb or sub-shrub up to 1.8 m tall with deep
(sometimes tuberous) roots and 3-foliate alternate leaves. It is distributed in Tropical Africa and
occurs in open and wooded ...
Knipholone cyclooxanthrone and an anthraquinone dimer with antiplasmodial activities from the roots of Kniphofia foliosa
(2013)
A new phenylanthrone, named knipholone cyclooxanthrone and a dimeric anthraquinone, 10-methoxy-10,7′-(chrysophanol anthrone)-chrysophanol were isolated from the roots of Kniphofia foliosa together with the rare naphthalene ...
Antiplasmodial and cytotoxic activities of the constituents of turraea robusta and turraea nilotica
(University of Nairobi, 2015-08)
Ethnopharmacological relevance
Turraea robusta and Turraea nilotica are African medicinal plants used for the treatment of a wide variety of diseases, including malaria. The genus Turraea is rich in limonoids and other ...
Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea
(Elsevier B.V., 2011)
The stem extract of Tephrosia purpurea showed anti plasmodial activity against the D6 (chloroquinesensitive)
and W2 (chloroquine-resistant) strains of Plasmodium /aldparum with 1(50 values of
10.47 ± 2.22 f.Lg/mland 12.06 ...
Crystal Structures and Cytotoxicity ofent-Kaurane-TypeDiterpenoids from TwoAspiliaSpecies
(University of Nairobi, 2018)
A phytochemical investigation of the roots ofAspilia plurisetaled to the isolationofent-kaurane-type diterpenoids and additional phytochemicals (1–23).The structures ofthe isolated compounds were ...