Now showing items 11-20 of 30
Optimization Of X-ray Fluorescence Elemental Analysis: An Example From Kenya
(University of Nairobi, 1998-07)
A systematic study and application of a radioisotope excited energy dispersive X-ray fluorescence analysis method to multi-elemental determination in Kenyan rock samples whose supporting matrices are of light elements is ...
Inhibition of c-Kit, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930
The quinoline domain of OSI-930, a dual inhibitor of receptor tyrosine kinases (RTKs) c-Kit and KDR, was modified in an effort to further understand the SAR of OSI-930, and the binding site characteristics of c-Kit and ...
Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia
Cancer-associated isocitrate dehydrogenase (IDH) mutations produce the metabolite 2-hydroxyglutarate (2HG), but the clinical utility of 2HG has not been established. We studied whether 2HG measurements in acute myeloid ...
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900
We determined the prognostic relevance of CD25 (IL-2 receptor-α) expression in 657 patients (≤ 60 years) with de novo acute myeloid leukemia (AML) treated in the Eastern Cooperative Oncology Group trial, E1900. We identified ...
The role of mutations in epigenetic regulators in myeloid malignancies
The role of mutations in epigenetic regulators in myeloid malignancies. Recent genomic studies have identified novel recurrent somatic mutations in patients with myeloid malignancies, including myeloproliferative ...
APPLICATION OF EULER DECONVOLUTION TECHNIQUE IN DETERMINING DEPTHS TO MAGNETIC STRUCTURES IN MAGADI AREA, SOUTHERN KENYA RIFT
Magadi area is located in the southern part of the Kenyan rift, an active continental rift that is part of the East African Rift system. Thermal manifestations in the form of hot springs in the northern and southern shores ...
The Paleomagnetism of Granites from Kenya
(University of Nairobi,, 1980)
New antitrypanosomal tetranotriterpenoids from Azadirachta Indica
(University of Nairobi, 1972-07)
Organic extracts of the leaves of Azadirachta indica A. Juss. yielded ten antitrypanosomal terpenoids. Three of these (1 – 3), are novel and are derivatives of nimbolide and nimbin. They were extracted from chloroform fraction ...