Faculty of Science & Technology (FST): Recent submissions
Now showing items 1481-1500 of 4283
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High-throughput screening and sensitized bacteria identify an M. tuberculosis dihydrofolate reductase inhibitor with whole cell activity.
(2012)Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is a bacterial pathogen that claims roughly 1.4 million lives every year. Current drug regimens are inefficient at clearing infection, requiring at ... -
Approaches to advancing blood safety through haemovigilance: a review.
(2009)BACKGROUND: Blood transfusion is always associated with some level of risk. Haemovigilance is a risk monitoring system integral to the practice of transfusion medicine whose ultimate purpose is to improve the quality ... -
Lupane triterpenoids from Acacia mellifera with cytotoxic activity.
(2007)Three new pentacyclic triterpenoids: (20R)-3-oxolupan-30-al (1), (20S)-3-oxolupan-30-al (2) and (20R)-28-hydroxylupen-30-al-3-one (3), along with (20S)-3beta-hydroxylupan-30-al (4), the latter previously described as a ... -
Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera
(2008)Acacia mellifera has been used widely in traditional African medicines against various diseases. Among the Kipsigis community of Kenya, water extracts from the plant is used for the treatment of skin diseases, coughs and ... -
Antimicrobial activity of Acacia mellifera extracts and lupane triterpenes.
(2009)ETHNOPHARMACOLOGICAL RELEVANCE: Acacia mellifera (Vahl) Benth (Leguminosae) is a subtropical medicinal plant that is widely used in traditional African medicines against various diseases such as pneumonia and malaria. AIM ... -
The sexual scripts of Kenyan young people and HIV prevention.
(2005)The scripting of sexual encounters among young people in Kenyan is described using results of 28 focus group discussions conducted with young people attending primary school standard 7, from four different ethnic groups ... -
Beta-2 microglobulin as a marker of HIV disease status in Nairobi, Kenya.
(1993)Serum beta-2 microglobulin (beta 2-M) has prognostic value similar to lymphocyte profiles for predicting disease progression in those infected with the human immunodeficiency virus (HIV). However, the relationship between ... -
Baseline STD prevalence in a community intervention trial of the female condom in Kenya
(2000)OBJECTIVE: We present baseline sexually transmitted disease (STD) prevalence rates from an ongoing intervention trial at Kenyan agricultural sites. METHODS: After gaining the cooperation of management, we identified ... -
Quasi-experimental evaluation of a national primary school HIV intervention in Kenya
(2007)This study examined the impact of a primary-school HIV education initiative on the knowledge, self-efficacy and sexual and condom use activities of upper primary-school pupils in Kenya. A quasi-experimental mixed ... -
Strength training in endurance runners.
(2010)This study examined effects of periodized maximal versus explosive strength training and reduced strength training, combined with endurance training, on neuromuscular and endurance performance in recreational endurance ... -
Skeletal neuromuscular and smooth muscle effects of whole venom of the green mamba, Dendroaspis angusticeps - I.
(1981)Dendroaspis angusticeps venom (75 micrograms/ml) caused an irreversible blockade of the directly as well as directly evoked contractions of the rat hemidiaphragm and indirectly evoked contractions of the chick biventer ... -
The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
(1989)Previously our laboratory (Rim et al., Int. J. Pharm. 32:79-84. 1986) described an in vitro blood-brain barrier (BBB) model consisting of cultured bovine brain microvessel endothelial cells (BMECs) grown onto regenerated ... -
Effect of induction-delivery and uterine-delivery on apgar scoring of the newborn
(1991)Very short or prolonged induction-delivery interval (i.e. less than 5 minutes or more than 15 minutes) and uterine-delivery interval of more than 90 seconds has a definite effect on the apgar scoring of a newborn especially ... -
A comparison of the effect on gastric emptying of alfentanil or morphine given during anaesthesia for minor surgery.
(1994)Twenty patients, scheduled for minor gynaecological surgery, were studied. Anaesthesia was induced with propofol and maintained with oxygen, nitrous oxide and enflurane. Patients were randomly allocated to two groups: group ... -
Right atrial electrocardiography: a technique for the placement of central venous catheters for chemotherapy or intravenous nutrition
(1994)Central venous catheters used for chemotherapy are usually sited so that the catheter tip lies in the superior vena cava. This study evaluated right atrial electrocardiography as a method of accurately placing the catheter ... -
pinous Process Fixation Devices for Instrumented Spinal Fusion.
(2013-09)Lumbar spinal fusion is a well-established surgical procedure for many spinal conditions. Posterior instrumentation may be added to provide immediate stabilization and improve fusion rates. Spinous process fixation, a type ...