Now showing items 1-3 of 3

    • Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort. 

      Landais, E; Huang, X; Havenar-Daughton, C; Murrell, B; Price, MA; Wickramasinghe, L; Ramos, A; Bian, CB; Simek, M; Allen, S; Karita, E; Kilembe, W; Lakhi, S; Inambao, M; Kamali, A; Sanders, EJ; Anzala, O; Edward, V; Bekker, LG; Tang, J; Gilmour, J; Kosakovsky-Pond, SL; Phung, P; Wrin, T; Crotty, S; Godzik, A; Poignard, P (2016)
      Broadly neutralizing antibodies (bnAbs) are thought to be a critical component of a protective HIV vaccine. However, designing vaccines immunogens able to elicit bnAbs has proven unsuccessful to date. Understanding the ...
    • Early antibody lineage diversification and independent limb maturation lead to broad hiv-1 neutralization targeting the env high-mannose patch. 

      MacLeod, DT; Choi, NM; Briney, B; Garces, F; Ver, LS; Landais, E; Murrell, B; Wrin, T; Kilembe, W; Liang, CH; Ramos, A; Bian, CB; Wickramasinghe, L; Kong, L; Eren, K; Wu, CY; Wong, CH; Kosakovsky, Pond S; Wison, IA; Burton, DR; Poignard, P (University of Nairobi, 2016)
      The high-mannose patch on HIV Env is a preferred target for broadly neutralizing antibodies (bnAbs), but to date, no vaccination regimen has elicited bnAbs against this region. Here, we present the development of a bnAb ...
    • Pregnancy and HIV Disease progression in an early infection cohort from five African countries. 

      Wall, KM; Rida, W; Haddad, LB; Kamali, A; Karita, E; Lakhi, S; Kilembe, W; Allen, S; Inambao, M; Yang, AH; Latka, MH; Anzala, O; Sanders, EJ; Bekker, LG; Edward, VA; Price, MA. (Unuversity of Nairobi, 2017)
      BACKGROUND: Understanding associations between pregnancy and HIV disease progression is critical to provide appropriate counseling and care to HIV-positive women. METHODS: From 2006 to 2011, women less than age 40 ...