Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 9550-9569 of 10378
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Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model.
(University of NairobiFaculty of medicine, 2007)Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded ... -
Synthesis of alpha-amyrin derivatives and their in vivo antihyperglycemic activity.
(University of NairobiFaculty of medicine, 2008)Ficus racemosa belongs to the family of Moraceae and is commonly known as 'Gular' in north India. Bio-activity guided isolation work on the fruits of F. racemosa resulted in the identification of antidiabetic active ... -
Synthesis of glucaminium-based ionic liquids and their application in the removal of boron from water.
(University of NairobiFaculty of medicine, 2012)A novel class of ionic liquids (ILs), exhibiting high selectivity towards boron species as well as the ability to phase separate from water, were synthesized from N-methyl-D-glucamine. The complexation of boric acid/borate ... -
Synthesis of Steroidal Indoxyl, and Derivatives from 3-ketosteroid
(University of NairobiDepartment of Pharmaceutical Chemistry, School of Pharmacy, College of Health Sciences, University of Nairobi., 2005)5&alpha-Androstan-17&beta-ol-3-one condenses with 2-nitrobenzaldehyde in alkaline conditions to give the steroidal indoxyl 17&beta-hydroxy-1-(3′-oxoindan-2′-yliden)-3-nor-1,2-secoandrostan-3-oic acid (I) which on refluxing ... -
Synthesis, antimalarial and antitubercular activity of acetylenic chalcones
(Department of Medicine. College of Health Sciences. University of Nairobi, 2010-02)A series of acetylenic chalcones were evaluated for antimalarial and antitubercular activity. The antimalarial data for this series suggests that growth inhibition of the W2 strain of Plasmodium falciparum can be imparted ... -
Synthesis, Biological Evaluation And Mechanistic Studies Of Totarol Amino Alcohol Derivatives As Potential Antimalarial Agents.
(University of NairobiDepartment of Biochemistry, 2012)Herein we report on the semisynthesis and biological evaluation of b-amino alcohol derivatives of the natural product totarol and other simple aromatic systems. All beta-amino alcohol derivatives of totarol exhibited higher ... -
Synthesis, Characterisation and Ion-binding Properties of Oxathiacrown Ethers Appended to [ru(Bpy)2]2+. Selectivity Towards Hg2+, Cd2+ and Pb2+
(University of Nairobi, 2018)A series of complexes with oxathiacrown ethers appended to a [Ru(bpy)2]2+ moiety have been synthesized and characterized using 1H NMR, 13C NMR, IR, electronic absorption and emission spectroscopes, mass spectrometry and ... -
Syphilis Control During Pregnancy: Effectiveness And Sustainability Of A Decentralized Program.
(University of NairobiCommunity Health ,School of Health Sciences, 2001)OBJECTIVES: This study sought to assess the performance, effectiveness, and costs of a decentralized antenatal syphilis screening program in Nairobi, Kenya. METHODS: Health clinic data, quality control data, and ... -
Syphilis control in pregnancy: decentralization of screening facilities to primary care level, a demonstration project in Nairobi, Kenya.
(Department of Obstetrics and Gynaecology, University of Nairobi, Kenya, 1995)A decentralized syphilis control program in pregnant women was implemented in nine Nairobi City Council antenatal clinics between July 1992 and August 1993, whereby pregnant women were screened for syphilis, treated before ... -
System dynamics model of cervical cancer vaccination and screening interventions in Kenya
(2014)Objectives This paper presents a simulation model for evaluating the possible effects of a screening and vaccination campaign against Human Papillomavirus [HPV] in Kenya. Method A System Dynamics model was developed ... -
Systematic analysis of STD control: an operational model.
(University of NairobiCollege of Health Sciences,University of Nairobi, 1998-07)BACKGROUND: Sexually transmitted diseases (STDs) enhance HIV transmission, and improved management of STD in primary health care decreases HIV incidence. In resource poor countries, those responsible for planning and ... -
A systematic review and meta-analysis of iliocapsularis muscle: an important landmark in orthopedic surgery
(University of Nairobi, 2021)Purpose: Iliocapsularis (IC) is a small muscle overlying the capsule of the hip joint. Although recent attention is being given to this muscle by orthopedic surgeons who encounter it during the anterior approach to total ... -
Systematic review and meta-analysis of the anatomical variants of the left colic artery.
(University of Nairobi, 2019)PURPOSE: To provide a comprehensive evidence-based assessment of the anatomical variations of the left colic artery (LCA). METHODS: A thorough systematic search of literature up until the 1st April 2019 was conducted ... -
Systematic review examining differences in HIV, sexually transmitted infections and health-related harms between migrant and non-migrant female sex workers.
(Department of Management Science, College of Humanities and Social Sciences, University of Nairobi, 2012-10)I have picked this evaluation because it focuses on the special needs of migrant female sex workers (FSWs), in particular those in Sub-Saharan Africa, where the prevalence of sexually transmitted infections (STls) and HIV ... -
A systematic review of interventions to improve prevention of mother-to-child HIV transmission service delivery and promote retention.
(University of Nairobi, 2016)INTRODUCTION: The success of prevention of mother-to-child transmission of HIV (PMTCT) is dependent upon high retention of mother-infant pairs within these programmes. This is a systematic review to evaluate the ... -
A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections
(University of Nairobi, 2022-03)Kenya's vision 2030 partly aims at ensuring adequate health care for all, and the integration of traditional healthcare practices into the national healthcare system would present a more rapid alternative towards the ... -
Systematic review of the performance and clinical utility of point of care HIV-1 RNA testing for diagnosis and care.
(University of Nairobi, 2019)BACKGROUND: Point of-care (POC) HIV-1 RNA tests which are accurate and easy to use with limited infrastructure are needed in resource-limited settings (RLS). We systematically reviewed evidence of POC test performance ... -
Systemic and Mucosal Concentrations of Nine Cytokines Among Individuals with Neisseria gonorrhoeae infection in Nairobi Kenya
(2022-03-16)Introduction The human-restricted sexually transmitted Neisseria gonorrhoeae (NG) has been shown to modulate the immune response against it and consequently the cytokines produced. The levels of cytokines in NG infection ... -
Systemic antibiotic prophylaxis in elective cesarean delivery.
(University of Nairobi.Department of Medicine, 1998-06)OBJECTIVE: To test the value of using prophylactic antibiotics at elective cesarean delivery. METHOD: One-hundred and twenty women delivered by elective cesarean in the absence of labor and before the rupture of membranes ... -
Systemic Cytokine Levels Show Limited Correlation with Risk of HIV-1 Acquisition.
(University of Nairobi, 2014-01)It has been hypothesized that immune activation and inflammation may increase HIV-1 susceptibility and that cytokines may be useful biomarkers for risk. Within a prospective cohort, we conducted a nested case-control ...
