Browsing Faculty of Health Sciences (FHS) by Author "Gachara, G"
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Assessing antigenic drift and phylogeny of influenza A (H1N1) pdm09 virus in Kenya using HA1 sub-unit of the hemagglutinin gene.
Opanda, S; Bulimo, W; Gachara, G; Ekuttan, C; Amukoye, E (University of Nairobi, 2020)Influenza A (H1N1) pdm09 virus emerged in North America in 2009 and has been established as a seasonal strain in humans. After an antigenic stasis of about six years, new antigenically distinct variants of the virus emerged ... -
Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya
Majanja, J; Njoroge, RN; Achilla, R,; Wurapa, EK,; Wadegu, M; Mukunzi, S; Mwangi, J; Njiri, J; Gachara, G; Bulimo, W (University of Nairobi.Department of Medical Laboratory Sciences, Kenyatta University, Nairobi, Kenya, 2013-05)We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008-July 2011. A total of 11,592 nasopharyngeal swabs were collected ... -
Neuraminidase Inhibitor activities on Influenza B isolates obtained in Kenya, 2011-2012
Jumba, G; Gachara, G; Bulimo, W (University of Nairobi, 2014)Introduction: Oseltamivir and zanamivir are neuraminidase inhibitors (NAIs) with important roles as drugs for prophylaxis and treatment of influenza. Whereas there have been reports of in vivo resistance of influenza B ... -
Origins, molecular epidemiology and genetic diversity of influenza a(H1N1)pdm09 virus in Kenya: a bayesian coalescent analysis
Gachara, G; Symekher, S; Otieno, M; Magana, J; Opot, B; Bulimo, W (University of Nairobi, 2014)Background: An influenza pandemic caused by a swine-origin influenza virus A/H1N1 [A(H1N1)pdm09] spread worldwide in 2009 and is estimated to have caused between 151,700 and 575,400 deaths globally. The spread of influenza ... -
Species and serotype diversity of human rhinoviruses from patients presenting with influenza like illness in Kenya in 2008
Milanoi, S; Opanda, S; Opot, B; Gachara, G; Ongus, J; Bulimo, W (University of Nairobi, 2014)Tract infections, the main cause of the common cold and recently have been associated with more serious respiratory infections. There are over 100 known serotypes of HRV, classified into 3 species (A, B and C). In Kenya, ... -
Whole genome characterization of human influenza A(H1N1)pdm09 viruses isolated from Kenya during the 2009 pandemic.
Gachara, G; Symekher, S; Otieno, M; Magana, J; Opot, B; Bulimo, W (Elsevier, 2016-06)An influenza pandemic caused by a novel influenza virus A(H1N1)pdm09 spread worldwide in 2009 and is estimated to have caused between 151,700 and 575,400 deaths globally. While whole genome data on new virus enables a ...