Browsing Faculty of Health Sciences (FHS) by Author "Jaoko Godfrey W."
Now showing items 1-3 of 3
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Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition
Iqbal, Shehzad M.; Ball, Terry B.; Levinson, Pauline; Maranan, Lillian; Jaoko Godfrey W.; Wachihi, Charles; Pak, Brian J.; Podust, Vladimir N.; Broliden, Kristina; Hirbod, Taha; Kaul, Rupert; Plummer, FA (2009)Globally, heterosexual intercourse is the primary route of HIV-1 (HIV) transmission. It follows that mechanisms that protect against HIV infection are likely operative at the genital mucosa. In HIV-resistant Kenyan sex ... -
Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression
Graham Susan M.; Rajwans Nimerta.; Jaoko Godfrey W.; Estambale Benson B.; McClelland R Scott.; Overbaugh Julie.; Liles W Conrad. (Institute of Tropical & Infectious Diseases, 2013)OBJECTIVE: We aimed to determine whether endothelial activation biomarkers increase after HIV-1 acquisition, and whether biomarker levels measured in chronic infection would predict disease progression and death in HIV-1 ... -
A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy
Graham, SM; Rajwans, N; Tapia, KA; Jaoko Godfrey W.; Estambale Benson B.; McClelland, RS; Overbaugh, J; Liles, WC (University of Nairobi.Department of Medical Microbiology, 2013-06)BACKGROUND: HIV-1-related inflammation is associated with increased levels of biomarkers of vascular adhesion and endothelial activation, and may increase production of the inflammatory protein angiopoietin-2 (ANG-2), an ...