Browsing Faculty of Health Sciences (FHS) by Author "Lacap, Philip"

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A Trim5alpha Exon 2 Polymorphism is Associated with Protection from HIV-1 Infection in Pumwani Sexworker Cohort

Price, Heather; Lacap, Philip; Tuff, Jeff; Charles Wachihi; Kimani, Joshua; Ball, Terry B; Luo, Ma; Plummer, Francis A (Department of Medical Microbiology, 2010)

Objective The innate immune component TRIM5α has the ability to restrict retrovirus infection in a species-specific manner. TRIM5α of some primate species restricts infection by HIV-1, while huTRIM5α lacks this specificity. ...