Browsing Faculty of Health Sciences (FHS) by Author "Machado, M"
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Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model
Singh, K; Okombo, J; Brunschwig, C; Ndubi, F; Barnard, L; Wilkinson, C; Njogu, PM; Njoroge, M; Laing, L; Machado, M; Prudêncio, M; Reader, J (ASC, 2017-02-23)Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds with improved in vivo ...