Browsing Faculty of Health Sciences (FHS) by Author "Mackelprang, Romel D"

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    • Barriers to Antiretroviral Initiation in HIV-1-Discordant Couples 

      Guthrie, Brandon L; Choi, Robert Y; Liu, Amy Y; Mackelprang, Romel D; Rositch, Anne F; Bosire, Rose; Manyara, Lucy; Gatuguta, Anne; Kiarie, James N; Farquhar, Carey (Department of Obstetrics and GynaecologyInstitute of Tropical and Infectious Diseases, 2011)
      BACKGROUND In Kenya and much of sub-Saharan Africa, nearly half of all couples affected by HIV are discordant. Antiretroviral therapy (ART) slows disease progression in HIV-1-infected individuals, and reduces transmission ...

    • Maternal Human Leukocyte Antigen - A*2301 Is Associated with Increased Mother-to-Child HIV-1 Transmission 

      Mackelprang, Romel D; Carrington, Mary; John-Stewart, Grace; Lohman-Payne, Barbara; Richardson, Barbra A; Wamalwa, Dalton; Gao, Xiaojiang; Majiwa, Maxwel; Mbori-Ngacha, DA; Farquhar, Carey (Department of Paediatrics, 2010)
      We examined associations between maternal HLA and vertical HIV-1 transmission in a perinatal cohort of 277 HIV-infected women in Nairobi. HLA class I genes were amplified using sequence-specific oligonucleotide probes and ...