Browsing Faculty of Health Sciences (FHS) by Author "Maclean, IW"
Now showing items 1-10 of 10
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Antimicrobial therapy of chancroid: an evaluation of five treatment regimens correlated with in vitro sensitivity
(University of Nairobi,Department of Medicine, 1983-03)One hundred fifty-one men with genital ulcer disease were assigned randomly to treatment with one of five oral antimicrobial regimens: (1) sulfadimidine (1 g four times daily for seven days); (2) tetracycline (500 mg four ... -
Antimicrobial therapy of chancroid: effectiveness of erythromycin
(University of Nairobi,Department of Medicine, 1983-10)The emergence of Haemophilus ducreyi resistant to multiple antibiotics has limited the effectiveness of sulfonamides and tetracycline for the therapy of chancroid. A randomized, double-blind study compared 10-day courses ... -
Cefotaxime treatment of Haemophilus ducreyi infection in Kenya.
(University of Nairobi,Department of Medicine, 1984-12)The authors conducted a double-blind randomized clinical trial comparing single-dose cefotaxime (1 g im) plus daily placebo injections with cefotaxime (1 g im on each of three days). Each regimen was given with probenicid ... -
The clinical diagnosis of genital ulcer disease in men in the tropics
(University of Nairobi,Department of Medicine, 1984-06)Since the clinical diagnosis of genital ulcers without laboratory confirmation is not reliable in developed countries, we postulated that clinical diagnosis alone would be no more reliable in developing countries. A ... -
Genetic diversity and mosaicism at the por locus of Neisseria gonorrhoeae.
(1999)The por genes of the predominant serovars of Neisseria gonorrhoeae circulating in a high-frequency transmitter core group located in Nairobi, Kenya, were examined for nucleotide sequence polymorphism. The level of por gene ... -
Human papillomavirus detection by penile site in young men from Kenya
(Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USADepartment of Medical microbiology, University of Nairobi, 2007)BACKGROUND: Limited data are available on whether sampling from the penile shaft or urethra increases detection of penile HPV infection in men beyond that found in the glans and coronal sulcus. METHODS: Within a ... -
Risk factors for Chlamydia trachomatis pelvic inflammatory disease among sex workers in Nairobi, Kenya
(University of Nairobi,Department of Medical Microbiology-, 1996)Among 302 female sex workers in Nairobi, Kenya, who were followed for 17.6 ± 11.1 months, 146 had one or more infections with Chlamydia trachomatis; 102 had uncomplicated cervical infection only, 23 had C. trachomatis ... -
Risk factors for Chlamydia trachomatis pelvic inflammatory disease among sex workers in Nairobi, Kenya
(College of Health Sciences, 1996)Abstract Among 302 female sex workers in Nairobi, Kenya, who were followed for 17.6 +/- 11.1 months, 146 had one or more infections with Chlamydia trachomatis; 102 had uncomplicated cervical infection only, 23 had C. ... -
Single-dose therapy of chancroid with trimethoprim-sulfametrole
(University of Nairobi,Department of Medicine, 1983-07)We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone ... -
Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase-positive Haemophilus ducreyi infection.
(University of Nairobi,Department of Medicine, 1982-09)Multiresistant strains of Haemophilus ducreyi, the aetiological agent of chancroid, are prevalent in Nairobi, Kenya, where tetracyclines and sulphonamides are no longer very effective in the treatment of chancroid. The ...
