Browsing Faculty of Health Sciences (FHS) by Author "Nagelkerke, Nico J"

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    • Effect of Baseline HIV Disease Parameters on CD4+ T Cell Recovery After Antiretroviral Therapy Initiation in Kenyan Women 

      McKinnon, Lyle R; Kimani, Makobu; Wachihi, Charles; Nagelkerke, Nico J; Muriuki, Festus K; Kariri, Anthony; Lester, Richard T; Gelmon, Lawrence; Ball, Blake T; Plummer, Francis A; Kaul, Rupert; Kimani, Joshua (Department of Medical Microbiology, 2010)
      Background Antiretroviral therapy (ART) for HIV infection reconstitutes the immune system and improves survival. However, the rate and extent of CD4+ T cell recovery varies widely. We assessed the impact of several ...

    • HIV-1 Clade D Is Associated with Increased Rates of CD4 Decline in a Kenyan Cohort 

      McKinnon, Lyle R; Nagelkerke, Nico J; Kaul, Rupert; Shaw, Souradet Y; Capina, Rupert; Luo, Ma; Kariri, Anthony; Apidi, Winnie; Kimani, Makobu; Wachihi, Charles; Jaoko, Walter; Anzala, A Omu; Kimani, Joshua; Ball, T Blake; Plummer, Francis A (University of Nairobi, 2012)
      HIV-1 is grouped phylogenetically into clades, which may impact rates of HIV-1 disease progression. Clade D infection in particular has been shown to be more pathogenic. Here we confirm in a Nairobi-based prospective female ...