Browsing Faculty of Health Sciences (FHS) by Author "Odera, Michael M"
Now showing items 1-3 of 3
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Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia
Stoute, José A; Odera, Michael M; Adhiambo, Christine; Otieno, Walter; Odhiambo, Collins O (Department of Biochemistry, 2008)Severe anemia due to Plasmodium falciparum malaria is a major cause of mortality among young children in western Kenya. The factors that lead to the age-specific incidence of this anemia are unknown. Previous studies have ... -
Red Blood Cell Immune Complex Binding Capacity in Children with Sickle Cell Trait (HbAS) Living in P. falciparum Malaria Holoendemic Region of Western
Otieno, Walter; Estambale, Benson; Odera, Michael M; Aluoch, Joash R; Stoute, José A (University of Nairobi Institute of Tropical and Infectious Diseases (UNITID), Kenya.US Army Medical Research Unit, Kenya Medical Research Institute, Kisumu, Kenya.Maseno University School of Medicine, Kisumu, KenyaDepartment of Medicine, Penn State University College of Medicine, Pennsylvania, USA., 2012)Aims: Malaria infection leads to the formation of circulating immune complexes (CICs) which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell ... -
Sickle Cell Trait (HbAS) is Associated with Increased Expression of Erythrocyte Complement Regulatory Proteins CR1 and CD55 Levels in Children
Stoute, José A; Aluoch, Joash R; Gondi, Stacey M O; Odera, Michael M; Estambale, Benson B A; Otieno, Walter (Institute of Tropical & Infectious Diseases, 2013)Erythrocyte complement regulatory proteins, complement receptor 1 (CR1) and decay accelerating factor (CD55) protect red blood cells (RBCs) from complement mediated damage by controlling complement activation cascade and ...