Browsing Faculty of Health Sciences (FHS) by Author "Yeda, R"
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The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011
Eyase, FL,; Akala, HM; Ingasia, L; Cheruiyot, A; Omondi, A,; Okudo, C; Juma, D; Yeda, R; Andagalu, B; Wanja, E; Kamau, E; Schnabel, D; Bulimo, W; Waters, NC; Walsh, DS; Johnson, JD (University of Nairobi.College of Health Sciences, University of Nairobi, Kenya, 2013)Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number of anti-malaria drugs. Pfmdr1 86Y and haplotypes at Pfcrt 72-76 have been linked to chloroquine ... -
Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012
Juma, DW; Omondi, AA; Ingasia, L; Opot, B; Cheruiyot, A; Yeda, R; Okudo, C; Muiruri, P; Ngalah, B; Chebon, LJ; Eyase, F; Johnson, J; Bulimo, WD; Akala, HM; Andagalu, B; Kamau, E (University of Nairobi, 2014)Background: Sulphadoxine-pyrimethamine (SP), an antifolate, was r eplaced by artemether-lumefantrine as the first-line malaria drug treatment in Kenya in 2004 due to the wide s pread of resistance. However, SP still remains ...