Browsing Faculty of Health Sciences (FHS) by Subject "Acyclovir, gastroretentive floating; bioavailability; simplex lattice mixture design; controlled drug release; dissolution models"
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Formulation design and in vitro characterization of gastroretentive floating acyclovir tablets.
(ECAJPS, 2023-11-20)Acyclovir is a thymidine kinase enzyme inhibitor used in the management of herpes zoster. Doses above 400mg exhibit poor bioavailability necessitating frequent administration to achieve the required therapeutic serum ...