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    • Lack of efficacy of isoniazid chemoprophylaxis in the preventions of tuberculosis in hiv - 1 infected adults 

      Hawken, M P; Merne, H K; Elliott, L C; Chakaya, J M; Morris, J S; Githui, W A; Juma, E S; Odhiambo, J A; Thiong'o, L N; Kimari, J N; Ngugi, Elizabeth N; Bwayo, JJ; Gilks, C F; Plummer, F A; Porter, J D; NunN, P P; McAdam, P W J; Keith (Department of Community Health, University of Nairobi, 2008)
      Background: Six months of daily isoniazid has been shown to be effective in preventing tuberculosis in the pre-HIV era. Because of underlying immune dysfunction and increased susceptibility to new infection this efficacy ...