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Investigating The Utility Of The Hiv-1 Bed Capture Enzyme Immunoassay Using Cross-sectional And Longitudinal Seroconverter Specimens From Africa.
(University of Nairobi, 2007)
BACKGROUND:
The identification of populations at risk of HIV infection is a priority for trials of preventive technologies, including HIV vaccines. To quantify incidence traditionally requires laborious and expensive ...
Sensitivity and specificity of HIV rapid tests used for research and voluntary counselling and testing
(2008-10)
Background: HIV rapid tests (RT) are a quick and non-technically demanding means
to perform HIV voluntary counselling and testing (VCT) but understanding their
limitations is vital to delivering quality VCT.
Objective: ...
Total lymphocyte count as a surrogate marker for CD4+ t cell count in initiating antiretroviral therapy at Kenyatta National Hospital, Nairobi.
(2007)
To evaluate the utility of Total Lymphocyte Count (TLC) as a surrogate marker for CD4 + T cell count in antiretroviral (ARV) treatment initiation in a Kenyan population of HIV seropositive patients at Kenyatta National ...
Phase 2A dose and route study of a DNA prime MVA boost vaccine candidate
(University of Nairobi, 2005)
Serologic testing algorithm for recent HIV seroconversion in estimating incidence of HIV-1 among adults visiting a VCT centre at a Kenyan tertiary health institution.
(University of Nairobi, 2009-05)
OBJECTIVE:
To determine HIV high risk groups among adults visiting Kenyatta National Hospital Voluntary Counselling and Testing Centre by use of Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS).
DESIGN:
A ...
Prevalence of HCV and HIV/HCV co-infection among volunteer blood donors and VCT clients
(2005)
To determine the prevalence of HCV infection and HCV/HIV co-infection among voluntary blood donors at the National Blood Transfusion Centre and clients at the Kenyatta National Hospital HIV-Voluntary Counseling and Testing ...
Elevation Of Immune Activation In Kenyan Women Is Associated With Alterations In Immune Function: Implications For Vaccine Development.
(University of Nairobi, 2004-11)
The infectious burden leading to immune activation can vary between different populations and lead to various immune dysfunctions. We compared the effect of immune activation on apoptosis and T cell function in HIV uninfected ...
Recombination following superinfection by HIV-1.
(University of nairobi, 2004)
Background: There is increasing recognition of recombinant HIV-1 strains globally, but it has been unclear whether recombination results from superinfection during untreated, chronic infection.
Objective: To search for ...
Pregnancy rates among female participants in phase I and phase IIA AIDS vaccine clinical trials in Kenya
(2009-09)
Background: Female participants in AIDS candidate vaccine clinical trials must agree to use effective contraception to be enrolled into the studies, and for a specified period after vaccination, since the candidate vaccines’ ...