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Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming
(2006)
Background: Two parallel studies evaluated safety and immunogenicity of a prophylactic HIV-1 vaccine in 192 HIV-seronegative, low-risk
volunteers. Modified vaccinia virus Ankara (MVA) and plasmid DNA (pTHr) expressed HIV-1 ...
Steroidal Indoxyls: Evaluation of Pk, values and anti-inflammatory activity
(2006)
Three steroidal indoxyls, 3-oxo-16,17-seco-16;.nor-l,4-androstadien-15-(7'-methoxy-2-indoxyliden)17-oic acid, 1-(2'-indoxyliden)-2-nor-l,2-secocholestan-3~ oic acid and 1-(5'- chloro-2-indoxyliden)-2-nor-l,2-secocholestan-3-oic ...
Prevalence and Antimicrobial susceptibility of staphylococcus aureus at the Kenyatta National Hospital, Nairobi.
(2006)
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus ...
Generation and characterization of a single-gene mouse-human chimeric antibody against hepatitis B surface antigen
(2006)
BACKGROUND: Antibody against hepatitis B surface antigen (HBsAg) is used for passive immunotherapy in certain cases of hepatitis B infection. The authors have earlier reported a high-affinity mouse monoclonal (5S) against ...
The Genetic Portrait Of An Outbreak Strain
(University of Nairobi, 2006-09)
Unique events in the genome of Mycobacterium tuberculosis, including deletions and IS6110 insertions, have been proposed to be responsible for the virulence phenotype of outbreak strains. Based on this premise, we determined ...
C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells
(C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells, 2006)
Dynamins are large GTPases that act in multiple vesicular trafficking events. We identified 14 loss-of-function alleles of the C. elegans dynamin gene, dyn-1, that are defective in the removal of apoptotic cells. dyn-1 ...
Prevalence of malocclusion among 12-15-year-olds in Moshi, Tanzania, using Bjork's criteria
(2006)
OBJECTIVE:
To assess the prevalence of malocclusion in 12-15 -year-olds in Moshi, Tanzania.
DESIGN:
Cross-sectional study.
SETTING:
Moshi Municipality, Kilimanjaro region, Tanzania.
SUBJECTS:
Two hundred and eighty ...
Nurse-Midwives' Attitudes towards Adolescent Sexual and Reproductive Health Needs in Kenya and Zambia
(2006)
Adolescent sexuality is a highly charged moral issue in Kenya and Zambia. Nurse-midwives are the core health care providers of adolescent sexual and reproductive health services but public health facilities are under-utilised ...