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Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition
(2009)
Globally, heterosexual intercourse is the primary route of HIV-1 (HIV) transmission. It follows that mechanisms that protect against HIV infection are likely operative at the genital mucosa. In HIV-resistant Kenyan sex ...
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
(University of Nairobi, 2009)
Signal transducer and activator of transcription 1 (STAT1) is activated in the inflammatory response to interferons. The MUC1 oncoprotein is overexpressed in human breast cancers. Analysis of genes differentially expressed ...
Oesophageal cancer and Kaposi's sarcoma in Malawi: a comparative analysis.
(University of Nairobi, 2009)
Given that oesophageal cancer (OC) is common in Malawi and its outcome is so
dismal, would it be pragmatic to promptly mitigate the effects of smoking,
alcohol and aflatoxins rather than seek a higher degree of local ...
Pressure ulcers presentations and management at Kenyatta National Hospital and Spinal Injury Hospital
(University of Nairobi, 2009)
Objective: To determine the presentation and management of patients with pressure ulcers.
Design: A prospective study.
Setting: The Kenyatta National Hospital (KNH) and National Spinal Injury Hospital (NSIH).
Subjects: ...
Reference Ranges for Some Biochemical Parameters in Adult Kenyans
(University of Nairobi,, 2009)
PURPOSE: To establish the reference ranges of some biochemical
parameters for adult Kenyan population.
METHODS: In a prospective involving 1100 healthy blood donors
(age: 18-55 yr) in Kenyatta National Hospital, Kenya ...
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
(University of Nairobi, 2009-11)
Human prostate cancers are dependent on the androgen receptor for their progression. The MUC1 heterodimeric oncoprotein is aberrantly overexpressed in prostate cancers; however, it is not known if MUC1 is of functional ...
Male Perspectives on Incorporating Men into Antenatal HIV Counseling and Testing
(2009)
Male partner involvement in antenatal voluntary HIV counseling and testing (VCT) has been shown to increase uptake of interventions to reduce the risk of HIV transmission in resource-limited settings. We aimed to identify ...
Genome-wide and fine-resolution association analysis of malaria in West Africa
(University of Nairobi., 2009)
We report a genome-wide association (GWA) study of severe malaria in The Gambia. The initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a replication study included 3,400 children. We ...