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The role of G protein gene GNB3 C825T Polymorphism in HIV-1 acquisition, progression and immune activation
(2012)
Background
The GNB3 C825T polymorphism is associated with increased G protein-mediated signal transduction, SDF-1α-mediated lymphocyte chemotaxis, accelerated HIV-1 progression, and altered responses to antiretroviral ...
Analgesic and anti-inflammatory activities of 9-Hexacosene and Stigmasterol isolated from Mondia whytei
(University of Nairobi, 2012)
The aim of the study was to ascertain the analgesic properties of Mondia whytei
roots and to isolate and characterize the active constituents. Bioactivity guided
fractionation of the chloroform root extract yielded ...
Antimicrobial activity of various extracts of the sea urchin Tripneustes gratilla (Echinoidea)
(University of Nairobi, 2012)
Background:
Marine invertebrates rely solely on innate immune
mechanisms, the cellular component of which is
characterized by hemocytes that phagocytize microbe
s and secrete soluble antimicrobial and cytotoxic substances. ...
In-Depth Analysis of Patient-Clinician Cell Phone Communication during the WelTel Kenya1 Antiretroviral Adherence Trial
(2012)
Background
The WelTel Kenya1 trial demonstrated that text message support improved adherence to antiretroviral therapy (ART) and suppression of HIV-1 RNA load. The intervention involved sending weekly messages to patients ...
The Prevalence of Stunting Is High in HIV-1–Exposed Uninfected Infants in Kenya
(2012)
As prevention of mother-to-child HIV-1 transmission (PMTCT) programs decrease the numbers of HIV-1–infected infants, it remains important to improve growth in HIV-1–exposed, uninfected (EU) infants. To determine the growth ...
Incidence and Correlates of HIV-1 RNA Detection in the Breast Milk of Women Receiving HAART for the Prevention of HIV-1 Transmission
(2012)
Background
The incidence and correlates of breast milk HIV-1 RNA detection were determined in intensively sampled women receiving highly active antiretroviral therapy (HAART) for the prevention of mother-to-child HIV-1 ...
Orbital cold abscesses with associated pansinusitis and bone involvement
(University of Nairobi,, 2012)
Orbital involvement in tuberculosis is rare even in areas where TB is endemic.1 Orbital TB is classified into five forms; classical periostitis, orbital soft tissue tuberculoma or cold abscess with no bone destruction, ...
The role of Cranio-Maxillofacial Surgeon in Cranio and neck trauma
(University of Nairobi, 2012)
Variant origin of the lateral circumflex femoral artery in a black Kenyan population
(University of Nairobi., 2012-02)
Variant origin of lateral circumflex femoral artery (FA) is important during harvesting of anterolateral thigh flaps, aortopopliteal by-pass, coronary artery grafting, and vascularised iliac transplant. The frequencies of ...
Evaluating Low Back Pain Patients for Prolapsed Interverbral Disc in a Kenyan Teaching Hospital
(University of Nairobi, 2012)
Background
Accurate evaluation of low back pain is essential for its rational management. The extent of use of clinical and imaging findings in identification of prolapsed intervertebral disk varies between centers. In ...