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Non-haematopoietic toxicity of anthracylines is more favourable than that of taxanes: experience from Nairobi
(University of Nairobi, 2012-02)
The isolation and clinical use of anthracyclines and taxanes were major breakthroughs in cancer chemotherapy. Their use has lead to cures and palliation of patients with diverse cancer types, notably breast cancer, malignant ...
Effects of delayed treatment on perforated peptic ulcers at Kenyatta National Hospital (KNH)
(2012)
Background: Perforations complicate up to 5-10% of peptic ulcer diseases1.
Mortality following peptic ulcer perforation can peak 29% 2, 3. Of the factors
that influence the outcome of peptic ulcer perforation, treatment ...
Role of grooming in reducing tick load in wild baboons (Papio cynocephalus)
(2012)
Nonhuman primate species spend a conspicuous amount of time grooming during social interactions,
a behaviour that probably serves both social and health-related functions. While the social implications
of grooming have ...
Risk Association between Human Leucocyte Antigens (HLA) and Cervical Neoplasia in Kenyan Women
(University of Nairobi,, 2012)
Cervical cancer is the second most common cause of cancer mortality among women worldwide (Franco et al, 2003). Epidemiological studies have shown a strong link between human papilloma virus (HPV) infection and the development ...
A pilot study assessing the prognostic value of CK18 and nDNA biomarkers in severe sepsis patients.
(University of Nairobi, 2012-03)
BACKGROUND AND OBJECTIVES:
Severe sepsis and septic shock have posed significant treatment challenges for many years. Recently, a number of circulating apoptosis biomarkers have emerged, such as full-length and caspase-cleaved ...
Reference values for some renal function parameters for adult population in north-rift valley, kenya.
(PMC, 2012)
A population based, cross-sectional study was carried out at Moi Teaching and Referral Hospital in collaboration with the Regional Blood Transfusion Center, North Rift. 367 participants (211 males and 156 females) were ...
The causes, treatment, and outcome of acute heart failure in 1006 Africans from 9 countries.
(University of Nairobi,, 2012-10)
BACKGROUND:
Acute heart failure (AHF) in sub-Saharan Africa has not been well characterized. Therefore, we sought to describe the characteristics, treatment, and outcomes of patients admitted with AHF in sub-Saharan ...
A prospective review of acute coronary syndromes in an urban hospital in sub-Saharan Africa. Shavadia J, Yonga G, Otieno H.
(University of Nairobi,, 2012-07)
OBJECTIVES:
To determine the epidemiology of acute coronary syndromes (ACS) in sub-Saharan Africa.
METHODS:
A prospective survey was carried out of all patients with a diagnosis of ACS who were admitted to the critical ...
Probiotics, prebiotics infant formula use in preterm or low birth weight infants: a systematic review.
(2012)
BACKGROUND:
Previous reviews (2005 to 2009) on preterm infants given probiotics or prebiotics with breast milk or mixed feeds focused on prevention of Necrotizing Enterocolitis, sepsis and diarrhea. This review assessed ...
Non-expression of androgen receptors in the carotid intimal medial zone
(University of Nairobi, 2012)
Androgens and oestrogens have been implicated in the noted gender differences in the increasing intimal
medial thickness. Oestrogens are protective in females while the role of androgens as male disadvantage
remains in ...