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Long-term Virologic Response and Genotypic Resistance Mutations in HIV-1 Infected Kenyan Children on Combination Antiretroviral Therapy
(2012)
Backround: HIV-infected children may require the use of combination antiretroviral treatment (cART) into adulthood. However, regimens are limited to first- and second-line in many African settings. Therefore, understanding ...
Two sugar isomers influence host plant acceptance by a cereal caterpillar pest.
(University of Nairobi,, 2012)
Plant sugars are often considered as primary feeding stimuli, conditioning host plant acceptance by herbivorous insects. Of the nine sugars identified from methanolic extracts of seven grass species, only turanose, a sucrose ...
Selective extraction of genotoxic impurities and structurally alerting compounds using polymeric ionic liquid sorbent coatings in solid-phase microextraction: Alkyl halides and aromatics.
(University of Nairobi, 2012)
A series of polymeric ionic liquids (PILs) possessing varied chemical makeup and composition were applied as selective solid-phase microextraction (SPME) sorbent coatings for the analysis of genotoxic impurities (GTIs) and ...
MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.
(University of Nairobi, 2012)
BACKGROUND:
The mucin 1 (MUC1) heterodimeric oncoprotein is overexpressed in human prostate cancers with aggressive pathologic and clinical features. However, few insights are available regarding the functional role of ...
MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells.
(University of Nairobi, 2012)
MUC1 is a heterodimeric glycoprotein that is overexpressed in breast cancers. The present studies demonstrate that the oncogenic MUC1 C-terminal subunit (MUC1-C) associates with the TCF7L2 transcription factor. The MUC1-C ...
Cellular polypropylene‐based piezoelectric films
(University of Nairobi,, 2012)
Cellular polypropylene-calcium carbonate based piezoelectric films were obtained using biaxial stretching and gas-mediated inflation followed by a corona discharge treatment using home-made devices. The obtained results ...
An Integrated approach for antiretroviral adherence and secondary HIVtransmission risk-reductionsupport by nurses in Kenya
(2012)
Ongoing antiretroviral therapy (ART) adherence
and secondary HIV transmission-risk reduction
(positive prevention) support are needed in resourcelimited
settings.We evaluated a nurse-delivered counseling
intervention ...
Age changes in the structure of human atrioventricular annuli
(2012)
Atrioventricular annuli are important in hemodynamic stability and support to tricuspid and mitral valves. Anatomical features of the annuli such as circumference, organization of connective tissue fibers, myocardium and ...
Compliance with antiretroviral regimens to prevent perinatal HIV-1 transmission in Kenya
(2012-06)
Objective: To compare compliance and infant HIV-1 infection risk at 6 weeks with
theThai-CDCandHIVNET-012antiretroviralregimensinafieldsetting.
Design: Randomizedclinicaltrial.
Setting: Tertiaryhospitalantenatalclinici ...
Cc868t Single nucleotide polymorphism and HIV Type 1 Disease progression among postpartum women in Kenya
(2012)
The C868T single nucleotide polymorphism in the CD4 receptor encodes an amino acid substitution of tryptophan
for arginine in the third domain. Previous studies suggest that C868T increases the risk of HIV-1
acquisition; ...