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Preventing HIV-1 Infection, More Epitope Is Not Better: Analysis of Gag Epitope of 2 HLA Alleles Associated with Different Outcome of HIV Infection
(2012)
Background: Current HIV vaccine candidates have been based on
the conventional views of viral infection and attempt to induce
broad T cell responses to HIV-1. Until now, the candidate vaccines
based on such approach ...
Outside Sexual Partnerships and Risk of HIV Acquisition for HIV Uninfected Partners in African HIV Serodiscordant Partnerships
(2012)
Background
As African countries scale up couples HIV testing, little is known about sexual behaviors and HIV risk for HIV uninfected partners in known HIV serodiscordant relationships.
Methods
We conducted a prospective ...
The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence
(2012-01)
The presence of depression in alcohol-dependent persons is likely to influence treatment process and outcomes. Identification of depression is important though not every depressed alcohol-dependent person requires treatment ...
Multiple Traumas, Postelection Violence, and Posttraumatic Stress Among Impoverished Kenyan Youth
(2012)
Research on posttraumatic stress disorder (PTSD) among youth has focused on specific subgroups from developed countries. Most of the world’s youth and war-like violence, however, is concentrated in developing countries, ...
The pattern and occurrence of ameloblastoma in adolescents treated at a university teaching hospital, in Kenya: a 13-year study
(2012-02)
Ameloblastoma presenting in the adolescent age group is rare with few studies documenting their occurrence.
AIM:
The aim of this study was to carry out an analysis of the pattern and occurrence of ameloblastoma in those ...
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012)
Background: CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in
Sub-Saharan Africa with the highest burden of HIV/AIDS are due to adopt these regimens. However, HIV-1 can ...
HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads
(2012)
There are limited data describing the functional characteristics of HIV-1 specific antibodies in breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to bind HIV-1 envelope, neutralize ...
A tale of two citizens: a State Attorney General and a hematologist facilitate translation of research into US Food and Drug Administration actions--a SONAR report.
(2012)
Pharmaceutical safety is a public health issue. In 2005, the Connecticut Attorney General (AG) raised concerns over adverse drug reactions in off-label settings, noting that thalidomide was approved to treat a rare illness, ...
Surgical significance of brachial arterial variants in a Kenyan population
(University of Nairobi, 2012)
Background: Knowledge of the variant anatomy of the brachial artery is important in radial arterial grafts for coronary bypass, percutaneous trans-radial approach to coronary angiography, angioplasty and flap surgery. These ...
Baboon spermatology: basic assessment and reproducibility in olive baboons (Papio anubis)
(University of Nairobi,, 2012)
Background
Development of a reproducible baboon in vitro fertilization (IVF) system require optimized and reproducible sperm parameters. The objective of this study was to document basic spermatology values and investigate ...