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Esophageal squamous dysplasia is common in asymptomatic Kenyans: a prospective, community-based, cross-sectional study.
(University of Nairobi, 2016)
OBJECTIVES:
Esophageal squamous cell carcinoma (ESCC) is endemic in east Africa and is a leading cause of cancer death among Kenyans. The asymptomatic precursor lesion of ESCC is esophageal squamous dysplasia (ESD). We ...
Bi treatment with hydralazine/nitrates vs. placebo in Africans admitted with acute HEart Failure (BA-HEF).
(University of Nairobi, 2016)
AIMS:
Patients with acute heart failure (HF) in Africa are rarely being treated with a hydralazine/nitrates combination. Therefore the effect of this treatment was studied here.
METHODS AND RESULTS:
The study was ...
Maternal highly active antiretroviral therapy reduces vertical cytomegalovirus transmission but does not reduce breast milk cytomegalovirus levels.
(University of Nairobi, 2016)
To evaluate the impact of highly active antiretroviral therapy (HAART) on CMV transmission and breast milk level in the context of maternal HIV. Specimens from a randomized trial conducted in Nairobi, Kenya between 2003-2005 ...
Perspectives of host faculty and trainees on international visiting faculty to paediatric academic departments in East Africa.
(University of Nairobi, 2016)
BACKGROUND:
Investments in faculty exchanges to build physician workforce capacity are increasing. Little attention has been paid to the expectations of host institution faculty and trainees. This prospective qualitative ...
Spiritual issues of people living and dying with advanced heart failure in Kenya: a qualitative serial interview study.
(University of Nairobi, 2016)
BACKGROUND:
Exploring patients' spiritual issues is vital for informing holistic care. The spiritual concerns of patients living and dying with advanced heart failure in sub-Saharan Africa remains unknown. Our aim was ...
Mapping international university partnerships identified by East African Universities as strengthening their medicine, nursing, and public health programs
(University of Nairobi, 2016)
Background
International university partnerships are recommended for increasing the capacity of sub-Saharan African universities. Many publications describe individual partnerships and projects, and tools are available ...
Determinants of Discontinuation of Contraceptive Methods among Women at Kenyatta National Hospital, Kenya
(2016)
Background: Contraceptive use prevalence in Kenya is at 58% according to the 2014 Kenya Demographic Health
Survey. Several factors lead to discontinuation and switch of contraceptives. Discontinuation rate as per ...
Treatment of chronic heart failure in adults at a referral hospital in Kenya: adverse drug reactions and determinants of adherence
(2016)
Background: Chronic Heart Failure is a major health problem with a prevalence of between 1 and 12% in USA and
Europe, and approximately 5.7% in Sub-Saharan Africa, and has socio-economic relevance owing to its high
prevalence, ...
Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort.
(2016)
Broadly neutralizing antibodies (bnAbs) are thought to be a critical component of a protective HIV vaccine. However, designing vaccines immunogens able to elicit bnAbs has proven unsuccessful to date. Understanding the ...
Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate
(2016)
Background: Depot medroxyprogesterone acetate (DMPA) is associated with HIV acquisition. We studied changes in vaginal microbiota and inflammatory milieu after DMPA initiation.
Methods: In a cohort of HIV-negative Kenyan ...