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Now showing items 101-110 of 178
Prolonged SARS-CoV-2 RNA detection in anal/rectal swabs and stool specimens in COVID-19 patients after negative conversion in nasopharyngeal RT-PCR test
(University of Nairobi, 2020)
Coronavirus disease 2019 (COVID‐19) is a rapidly escalating pandemic that has spread to many parts of the world. Current data available on COVID‐19 would suggest that SARS‐CoV‐2 virus is shed through the gastrointestinal ...
Chewable Antacid Tablets: Are Disintegration Tests Relevant?
(University of Nairobi, 2020)
A recently published FDA guidance on chewable tablets has addressed the quality attributes of this class of dosage forms. This study evaluated disintegration as a quality attribute for a number of commercially available ...
Factors associated with time in therapeutic range among patients on oral anticoagulation therapy in a tertiary teaching and referral hospital in Kenya
(East Cent. Afr. J. Pharm. Sci, 2020-02-03)
Oral anticoagulation with warfarin is challenging owing to the drug’s
narrow therapeutic index. Achievement of therapeutic range ensures
safety and efficacy of warfarin therapy. A retrospective study of four
hundred and ...
Product evaluation of carbamazepine 200mg controlled release tablets using an in vitro-in vivo correlation simulation mode
(East Cent. Afr. J. Pharm. Sci, 2020-09-03)
Evaluation of the dissolution characteristics of drugs and their bioavailability
can be conducted using an in vitro-in vivo correlation model. This can help in
assessing the products available in the market for quality. ...
Prevalence and antimicrobial susceptibility of bacteria implicated in neonatal sepsis at Pumwani Maternity Hospita
(East Cent. Afr. J. Pharm. Sci, 2020-09-03)
Neonatal sepsis is one of the most common causes of morbidity and mortality among
infants in developing countries. The etiology and antimicrobial sensitivity patterns of
bacteria responsible vary in different hospitals. ...
Plasmid mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates from Kenya
(University of Nairobi, 2020)
Background: Treatment of gonorrhea is complicated by the development of antimicrobial resistance in Neisseria gonorrhoeae (GC) to the antibiotics recommended for treatment. Knowledge on types of plasmids and the antibiotic ...
Knowledge and practices regarding Middle East Respiratory Syndrome Coronavirus among camel handlers in a Slaughterhouse, Kenya, 2015
(University of Nairobi, 2020)
Dromedary camels are implicated as reservoirs for the zoonotic transmission of Middle East Respiratory Syndrome coronavirus (MERS-CoV) with the respiratory route thought to be the main mode of transmission. Knowledge and ...
The Clinical Profile of Severe Pediatric Malaria in an Area Targeted for Routine RTS,S/AS01 Malaria Vaccination in Western Kenya
(University of Nairobi, 2020)
Background
The malaria prevalence has declined in western Kenya, resulting in the risk of neurological phenotypes in older children. This study investigates the clinical profile of pediatric malaria admissions ahead of ...
Metabolic syndrome and 10-year cardiovascular risk among HIV-positive and HIV-negative adults
(University of Nairobi, 2020)
To determine the prevalence and correlates of metabolic syndrome (MetS) and compare 10-year cardiovascular disease (CVD) risk among Kenyan adults with and without HIV infection.
We conducted a cross-sectional study among ...
Mentorship in African health research training programs: an exploratory study of fogarty international center programs in Kenya and Uganda
(University of Nairobi, 2020)
Introduction: Mentorship is a critical element of capacity‑building for health research as it can support career counseling, promote interest
in health research and build professional networks. Few studies of mentorship ...