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Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya
(University of Nairobi., 2013-05)
We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008-July 2011. A total of 11,592 nasopharyngeal swabs were collected ...
Sex differences in the cranial and orbital indices for a black Kenyan population
(university of Nairobi, 2013)
Craniometric parameters including cranial and orbital indices have been employed to determine the sex of a person in forensic medicine. These parameters are usually population specific. However, they have not been documented ...
Moving beyond essential interventions for reduction of maternal mortality (the WHO Multicountry Survey on Maternal and Newborn Health): a cross-sectional study
(University of Nairobi, 2013)
Background: We report the main findings of the WHO Multicountry Survey on Maternal and Newborn Health (WHOMCS), which aimed to assess the burden of complications related to pregnancy, the coverage of key maternal health ...
HIV infection in uncircumcised men is associated with altered CD8 T cell function but normal CD4 T cell numbers in the foreskin
(2013-11)
Background. HIV-infected (HIV+) men are more susceptible to sexually transmitted infections (STIs), and may also become superinfected by HIV. We hypothesized that HIV induces immune alterations in the foreskin that may ...
A joint model for longitudinal continuous and time-to-event outcomes with direct marginal interpretation
(Wiley, 2013)
Joint modeling of various longitudinal sequences has received quite a bit of attention in recent times. This paper proposes a so-called marginalized joint model for longitudinal continuous and repeated time-to-event outcomes ...
Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation.
(University of Nairobi, 2013-09)
Mucosal Th17 cells maintain the gut epithelial barrier and prevent invasion by luminal bacteria through a delicate balance of immunosuppressive and proinflammatory functions. HIV infection is characterized by mucosal Th17 ...
Non-invasive sampling of schistosomes from humans requires correcting for family structure.
(2013)
For ethical and logistical reasons, population-genetic studies of parasites often rely on the non-invasive sampling of offspring shed from their definitive hosts. However, if the sampled offspring are naturally derived ...
Evidence for Efficient Vertical Transfer of Maternal HIV-1 Envelope-Specific Neutralizing Antibodies but No Association of Such Antibodies With Reduced Infant Infection
(University of Nairobi, 2013-10-01)
Little is known about the efficiency of vertical transfer of HIV-1-specific antibodies. Antibody levels in plasma from 60 mother-infant pairs near the time of birth, including 14 breast-feeding transmission pairs, were ...
School snacks decrease morbidity in Kenyan schoolchildren: a cluster randomized, controlled feeding intervention trial
(2013)
OBJECTIVE:
To examine the effects of three different school snacks on morbidity outcomes
DESIGN: Twelve schools were randomized to either one of three feeding groups or a Control group. There were three schools per group ...
Differences in response to imatinib between gastrointestinal stromal tumours involving the liver and tumours that do not: experience from Nairobi
(2013-05)
Introduction:
More than 60% of gastrointestinal stromal tumours (GISTs) arise from the stomach and about 20% from the small intestine. About 95% of GISTs express kit receptor tyrosine kinase (CD117), which is used for ...