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Cervical Shedding Of Cytomegalovirus In Human Immunodeficiency Virus Type 1-infected Women.
(University of Nairobi, 1999)
Cervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort ...
Breast-milk infectivity in human immunodeficiency virus type 1-infected mothers.
(University of Nairobi., 2003-03)
Human immunodeficiency virus type 1 (HIV-1) is transmitted through blood, genital secretions, and breast milk. The probability of heterosexual transmission of HIV-1 per sex act is.0003-.0015, but little is known regarding ...
Acute HIV infection among Kenyan infants.
(University of Nairobi., 2008-01)
BACKGROUND:
Clinical signs and symptoms of acute human immunodeficiency virus (HIV) infection in infants are not well characterized.
METHODS:
Serial clinical assessments and HIV PCR assays were conducted in a cohort of ...
FCGR2A and FCGR3A Genotypes in Human Immunodeficiency Virus Mother-to-Child Transmission.
(University of Nairobi, 2015-10)
Background. Fc-mediated effector functions have been suggested to influence human immunodeficiency virus (HIV) acquisition and disease progression. Analyzing the role of host Fc gamma receptor (FcγR) polymorphisms on HIV ...
Selenium deficiency is associated with shedding of HIV-1--infected cells in the female genital tract.
(2001)
Objective: To assess the relation between selenium deficiency and vaginal or cervical shedding of HIV-1-infected cells.
Design: Cross-sectional study of 318 HIV-1 seropositive women in Mombasa, Kenya.
Methods: Vaginal ...
Vitamin A supplementation and human immunodeficiency virus type 1 shedding in women: results of a randomized clinical trial.
(2002)
Observational studies have associated vitamin A deficiency with vaginal shedding of human immunodeficiency virus (HIV) type 1-infected cells and mother-to-child HIV-1 transmission. To assess the effect of vitamin A ...
Injectable contraceptive use and genital ulcer disease during the early phase of HIV-1 infection increase plasma virus load in women.
(2004)
We examined the association between host factors present near the time of human immunodeficiency virus type 1 (HIV-1) acquisition and subsequent virus loads, in a prospective cohort study of women in Mombasa, Kenya. Women ...
Treatment Of Cervicitis Is Associated With Decreased Cervical Shedding Of Hiv-1. AIDS
(2001-01-05)
OBJECTIVE: To determine whether cervical mucosal shedding of HIV-1 RNA and HIV-1 infected cells decreases following successful treatment of cervicitis. DESIGN: Prospective interventional study. SETTING: Sexually Transmitted ...
Phylogenetic evaluation of Kenyan HIV type 1 isolates.AIDS Res Hum Retroviruses
(University of Nairobi, 1997-04)
Diversity among global isolates of HIV-1 presents a formidable challenge for vaccine development. As distinct clades of the virus are recognized, it will be important to monitor their geographic distribution and divergence. ...
Efficient isolation of human immunodeficiency virus type 1 RNA from cervical swabs
(University of Nairobi, 1998-08)
An efficient method for the isolation of human immunodeficiency virus type 1 (HIV-1) nucleic acids from dry cervical swabs was developed. HIV-1 gag and env were detected in 96% (25 of 26) and 81% (21 of 26), respectively, ...