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Now showing items 10281-10290 of 10378
Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother
(University of Nairobi, 2023)
Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious diseases. One setting where this has consistently been observed is in ...
Individual-, Interpersonal- and Institutional-Level Factors Associated with HIV Stigma Among Youth in Kenya
(University of Nairobi, 2023)
HIV stigma remains a barrier in achieving optimal HIV treatment. We studied the prevalence and predictors of HIV stigma among adolescents and youth with HIV (AYWHIV) ages 15-24 years in Western Kenya. Of 1011 AYWHIV, 69% ...
Nurses' and midwives' participation and utilization of health-related research in Kenya: Implications for evidence-based practice
(University of Nairobi, 2023)
Objective: To assess the level of participation of nurses and midwives in health-related research, determine the status of utilization of research to inform nursing and midwifery practice in Kenya, and explore perspectives ...
Hydroxychloroquine reduces T cells activation recall antigen responses
(University of Nairobi, 2023)
Background: In the context of the current COVID-19 pandemic, there is still limited information about how people suffering from autoimmune diseases respond to the different COVID vaccines. The fact that they are taking an ...
Cutaneous signs of rheumatic diseases in skin of colour: are we failing our patients?
(University of Nairobi, 2023)
Comparison of nucleocapsid and spike antibody ELISAs for determining SARS-CoV-2 seropositivity in Kenyan women and infants
(University of Nairobi, 2023)
A multitude of enzyme-linked immunosorbent assays (ELISAs) has been developed to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies since the coronavirus disease 2019 pandemic started in late ...
Coenzyme Q10 exhibits anti-inflammatory and immune-modulatory thereby decelerating the occurrence of experimental cerebral malaria
(University of Nairobi, 2023)
Cerebral Malaria (CM) is associated with the complex neurological syndrome, whose pathology is mediated by severe inflammatory processes following infection with Plasmodium falciparum. Coenzyme-Q10 (Co-Q10) is a potent ...
HIV acquisition prior to entry into formal sex work: inference from next-generation viral sequencing
(University of Nairobi, 2023)
Objective: To infer the timing of HIV acquisition in relation to self-reported events in the sexual life course of adolescent girls and young women (AGYW) who self-identify as female sex workers (FSW) in Mombasa, ...
Risk of autism spectrum disorder and association of its symptoms with psychiatric and substance use disorders in non-clinical student sample in Kenya: cross-sectional study
(University of Nairobi, 2023)
Background: The prevalence and patterns of autism spectrum disorder (ASD) symptoms/traits and the associations of ASD with psychiatric and substance use disorders has not been documented in non-clinical students in Sub-Saharan ...
Nursing and midwifery research priorities for Kenya: Results from a national Delphi survey
(University of Nairobi, 2023)
Background: The International Council of Nurses and the World Health Organization have prioritized evidence-based nursing and midwifery practice derived from nurse-led research. However, in a low-resource country like ...