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Now showing items 1-10 of 38
Phase 2A dose and route study of a DNA prime MVA boost vaccine candidate
(University of Nairobi, 2005)
Serologic testing algorithm for recent HIV seroconversion in estimating incidence of HIV-1 among adults visiting a VCT centre at a Kenyan tertiary health institution.
(University of Nairobi, 2009-05)
OBJECTIVE:
To determine HIV high risk groups among adults visiting Kenyatta National Hospital Voluntary Counselling and Testing Centre by use of Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS).
DESIGN:
A ...
Incident Herpes Simplex Virus Type 2 Infection Increases the Risk of Subsequent Episodes of Bacterial Vaginosis.
(University of Nairobi, 2013-11)
Herpes simplex virus type 2 (HSV-2) infected women have a higher prevalence of bacterial vaginosis (BV) compared to HSV-2-seronegative women. To explore the temporal association between these conditions, we evaluated the ...
Elevation of Soluble Intercellular Adhesion Molecule-1 Levels, but Not Angiopoietin 2, in the Plasma of Human Immunodeficiency Virus-Infected African Women with Clinical Kaposi Sarcoma.
(2014-07)
Circulating levels of endothelial activation biomarkers are elevated in during infection with human immunodeficiency virus 1 (HIV-1) and may also be increased in Kaposi sarcoma (KS). We compared 23 HIV-1-seropositive women ...
Effect of Vaginal Washing on Lactobacillus Colonisation in HIV-Negative Kenyan Women
(University of Nairobi, 2013)
Background Vaginal washing has been associated with an
increased risk of bacterial vaginosis (BV) and a decreased likelihood
of vaginal Lactobacillus colonisation. We sought to determine
whether a lower prevalence of ...
αEβ7, α4β7 and α4β1 integrin contributions to T cell distribution in blood, cervix and rectal tissues: Potential implications for HIV transmission
(University of Nairobi, 2018)
Cell surface expression of α4β7, α4β1 and αEβ7 integrins play a key role in T cell distribution. Understanding the contribution of integrins to the density and ratios of CD4+: CD4negT cell at the portals of entry for HIV ...
Circumcision status at HIV infection is not associated with plasma viral load in men: analysis of specimens from a randomized controlled trial.
(University of Nairobi, 2018)
Background
Male circumcision provides men with approximately 60% protection from acquiring HIV infection via heterosexual sex, and has become a key component of HIV prevention efforts in sub-Saharan Africa. Possible ...
Association between non-barrier modern contraceptive use and condomless sex among HIV-positive female sex workers in Mombasa, Kenya: A prospective cohort analysis.
(University of Nairobi, 2017)
BACKGROUND:
As access to antiretroviral therapy in sub-Saharan Africa continues to expand, more women with HIV can expect to survive through their reproductive years. Modern contraceptives can help women choose the timing ...
Hiv-1 Superinfection Is Associated With An Accelerated Viral Load Increase But Has A Limited Impact On Disease Progression.
(University of Nairobi, 2014)
OBJECTIVE
HIV-1 superinfection occurs frequently in high-risk populations, but its clinical consequences remain poorly characterized. We undertook this study to determine the impact of HIV-1 superinfection on disease ...
Prospective Study Of Correlates Of Vaginal Lactobacillus Colonisation Among High-risk Hiv-1 Seronegative Women
(University of Nairobi, 2009)
Objective: Vaginal colonisation with Lactobacillus species is characteristic of normal vaginal ecology. The absence of vaginal lactobacilli, particularly hydrogen peroxide (H2O2)-producing isolates, has been associated ...