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Fertility rate of epileptic women at Kenyatta National Hospital.
(2008)
Reproductive health issues of women with epilepsy (WWE) are complex and multifaceted, and both epilepsy and antiepileptic drug (AEDs) use may alter fertility and pregnancy outcomes in these women.
To determine the ...
Cryptococcal hepatitis and meningitis in a patient with acquired immunodeficiency syndrome: a case report.
(1989)
A case of cryptococcal hepatitis is described in a patient with Human Immunodeficiency Virus (HIV) infection. There has been no previous reports of this in the East African literature. A review of world literature showed ...
High sensitivity c-reactive protein in type 2 diabetic patients with and without the metabolic syndrome
(2008)
Objective: To describe the distribution of serum high-sensitivity C-reactive protein (hsCRP) in type 2 diabetes mellitus outpatients, and relate it to cardiovascular disease risk.
Design: Cross-sectional descriptive ...
Observer variability of an angiographic grading scale used for the assessment of intracranial aneurysms treated with flow-diverting stents.
(2013)
Abstract
Novel angiographic grading scales for the assessment of intracranial aneurysms treated with flow-diverting stents have been recently developed because previous angiographic grading scales cannot be applied to ...
Serum Vitamin D Profile In Black African Men with Prostate Cancer at Tertiary Referral Facility in Sub-Saharan Africa
(University of Nairobi,, 2014)
Background:
Considerable epidemiological, in vitro, in vivo and clinical data support an association between
vitamin D deficiency and prostate cancer
risk and
outcome.
Few studies have examined
t
his association
...
Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase.
(University of Nairobi, 2000-05)
The pH optima of family 11 xylanases are well correlated with the nature of the residue adjacent to the acid/base catalyst. In xylanases that function optimally under acidic conditions, this residue is aspartic acid, whereas ...
Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model.
(University of Nairobi, 2007)
Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded ...
Parasitic diseases: Liposomes and polymeric nanoparticles versus lipid nanoparticles.
(University of Nairobi, 2007)
Parasitic diseases such as malaria, leishmaniasis, and trypanosomiasis represent a significant global burden and pose a great challenge to drug discovery and delivery scientists due to their intracellular nature and ...
Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
(University of Nairobi, 2001)
Previous studies of the low molecular mass family 11 xylanase from Bacillus circulans show that the ionization state of the nucleophile (Glu78, pK(a) 4.6) and the acid/base catalyst (Glu172, pK(a) 6.7) gives rise to its ...
Solid lipid nanoparticles (SLN) of tretinoin: potential in topical delivery.
(University of Nairobi, 2007)
The objective of this investigation was to develop solid lipid nanoparticles (SLN) of tretinoin (TRE) with the help of facile and simple emulsification-solvent diffusion (ESD) technique and to evaluate the viability of an ...