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Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.

Baeten, JM; Donnell, D; Mugo, NR; Ndase, P; Thomas, K; Campbell, J; Wangisi, J; Tappero, JW; Bukusi, EA; Cohen, CR; Katabira, E; Ronald, A; Tumwesigye, E; Were, E; Fife, KH; Kiarie, J; Farquhar, C; John-Stewart, G; Kidoguchi, L; Coombs, RW; Hendrix, C; Marzinke, MA; Frenkel, L; Haberer, JE; Bangsberg, D; Celum, C (2014)

Abstract BACKGROUND: Antiretroviral pre-exposure prophylaxis (PrEP), with daily oral tenofovir disoproxil fumarate or tenofovir disoproxil fumarate in combination with emtricitabine, has been shown to be efficacious ...

Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.

Celum, C; Corey, L; Ridzon, R; Barnes, L; McElrath, MJ; Whittington, WL; Morrow, R; Coombs, RW; Thomas, KK; Campbell, MS; Stevens, W; Vwalika, B; Rees, H; Delany, S; Kanweka, W; Karita, E; Kayitenkore, K; Inambao, M; Allen, S; Coetzee, D; Kapiga, S; Manongi, R; McIntyre, JA; Gray, GE; G, de Bruyn; Fife, KH; Were, E; Essex, M; Makhema, J; Stewart, GJ; Farquhar, C; Kiarie, J; Ronald, A; Katabira, E; Cohen, CR; Bukusi, EA; Hughes, JP; Mullins, JI; Baeten, JM; Mujugira, A; Mugo, N; Wang, RS; Magaret, AS; Lingappa, JR; Wald, A (2010)

Most persons who are infected with human immunodeficiency virus type 1 (HIV-1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated and is associated with increased plasma and genital ...

Pre-exposure prophylaxis for HIV-1 prevention does not diminish the pregnancy prevention effectiveness of hormonal contraception.

Baeten, JM; Celum, C; Kiarie, J; Mujugira, A; Were, E; Mugo, NR; Donnell, D; Bukusi, EA; Ronald, A; Heffron, R; Murnane, PM (University of Nairobi, 2014)

BACKGROUND: For women at risk of HIV-1, effective contraception and effective HIV-1 prevention are global priorities. METHODOLOGY: In a clinical trial of pre-exposure prophylaxis (PrEP) for HIV-1 prevention in ...

Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraception.

Heffron, R; Mugo, N; Were, E; Kiarie, J; Bukusi, EA; Mujugira, A; Frenkel, LM; Donnell, D; Ronald, A; Celum, C; Baeten, JM (2014)

OBJECTIVE:: To evaluate preexposure prophylaxis (PrEP) efficacy for HIV-1 prevention among women using depot medroxyprogesterone acetate (DMPA) for contraception and men whose HIV-1-infected partners use DMPA. DESIGN ...