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Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission.
(Univesity of Nairobi, 2011-04)
High plasma HIV-1 RNA concentrations are associated with an increased risk of HIV-1 transmission. Although plasma and genital HIV-1 RNA concentrations are correlated, no study has evaluated the relationship between genital ...
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
(2010)
Most persons who are infected with human immunodeficiency virus type 1 (HIV-1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated and is associated with increased plasma and genital ...
Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk.
(Univesity of Nairobi, 2010-09)
BACKGROUND:
The risk of sexual transmission of HIV-1 is strongly associated with the level of HIV-1 RNA in plasma making reduction in HIV-1 plasma levels an important target for HIV-1 prevention interventions. A ...