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Cefotaxime treatment of Haemophilus ducreyi infection in Kenya.
(University of Nairobi,, 1984-12)
The authors conducted a double-blind randomized clinical trial comparing single-dose cefotaxime (1 g im) plus daily placebo injections with cefotaxime (1 g im on each of three days). Each regimen was given with probenicid ...
Antimicrobial therapy of chancroid: effectiveness of erythromycin
(University of Nairobi,, 1983-10)
The emergence of Haemophilus ducreyi resistant to multiple antibiotics has limited the effectiveness of sulfonamides and tetracycline for the therapy of chancroid. A randomized, double-blind study compared 10-day courses ...
The clinical diagnosis of genital ulcer disease in men in the tropics
(University of Nairobi,, 1984-06)
Since the clinical diagnosis of genital ulcers without laboratory confirmation is not reliable in developed countries, we postulated that clinical diagnosis alone would be no more reliable in developing countries. A ...
Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase-positive Haemophilus ducreyi infection.
(University of Nairobi,, 1982-09)
Multiresistant strains of Haemophilus ducreyi, the aetiological agent of chancroid, are prevalent in Nairobi, Kenya, where tetracyclines and sulphonamides are no longer very effective in the treatment of chancroid. The ...
Single-dose therapy of chancroid with trimethoprim-sulfametrole
(University of Nairobi,, 1983-07)
We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone ...
Antimicrobial therapy of chancroid: an evaluation of five treatment regimens correlated with in vitro sensitivity
(University of Nairobi,, 1983-03)
One hundred fifty-one men with genital ulcer disease were assigned randomly to treatment with one of five oral antimicrobial regimens: (1) sulfadimidine (1 g four times daily for seven days); (2) tetracycline (500 mg four ...