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Characteristics Associated with Disclosure Status to Sexual Partners among Kenyan Women
(University of Nairobi, 2020)
Background: Kenya has the fourth-largest HIV epidemic across the globe. Disclosure of HIV-positive status plays a critical role in the prevention of HIV transmission. Disclosure, specifically to sexual partners, has been ...
Psychosocial Factors, Condomless Sex, and Detectable Viral Load in HIV-Positive Women in Serodiscordant Couples in Nairobi, Kenya
(University of Nairobi, 2020)
This prospective study of HIV-positive Kenyan women in serodiscordant couples examined relationships between psychosocial factors, viral suppression, and condomless sex. Participants were screened for alcohol use disorders ...
Impact of preconception vaginal microbiota on women's risk of spontaneous preterm birth: protocol for a prospective case-cohort study
(University of Nairobi, 2020)
Introduction: Bacterial vaginosis (BV) and vaginal microbiota disruption during pregnancy are associated with increased risk of spontaneous preterm birth (SPTB), but clinical trials of BV treatment during pregnancy have ...
Growth patterns and their contributing factors among HIV-exposed uninfected infants
(University of Nairobi, 2020)
With expanded HIV treatment and prevention programmes, most infants born to HIV-positive women are uninfected, but the patterns and determinants of their growth are not well described. This study aimed to assess growth ...
Setting priorities for patient-centered surveillance of drug-resistant infections
(University of Nairobi, 2020)
Methods: A priority-setting process (PSP) was launched to define priorities for patient-centered antimicrobial resistance (AMR) surveillance and research in low- and middle-income countries (LMICs). A list of uncertainties ...
What Could "Fair Allocation" during the Covid-19 Crisis Possibly Mean in Sub-Saharan Africa?
(University of Nairobi, 2020)
The Covid-19 pandemic has sparked rapid and voluminous production of bioethics commentary in popular media and academic publications. Many of the discussions are new twists on an old theme: how to fairly allocate scarce ...
Zika Virus Circulates at Low Levels in Western and Coastal Kenya
(University of Nairobi, 2020)
Background: Zika virus (ZIKV) was discovered over 70 years ago in East Africa, but little is known about its circulation and pathogenesis there.
Methods: We screened 327 plasma samples collected 2-12 months after febrile ...
Intimate Partner Violence, Human Rights Violations, and HIV among Women in Nairobi, Kenya
(University of Nairobi, 2020)
This study presents qualitative results from a mixed-method investigation conducted between May and August 2012 into the prevalence and consequences of four forms of intimate partner violence among women living with HIV ...
Specificity of CD8+ T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya
(University of Nairobi, 2020)
Sub-Saharan Africa carries the biggest burden of the human immunodeficiency virus type 1 (HIV-1)/AIDS epidemic and is in an urgent need of an effective vaccine. CD8+ T cells are an important component of the host immune ...
Vaginal washing behaviour and fecundability among Kenyan women in a prospective preconception cohort
(University of Nairobi, 2022-03)
Background: Intravaginal washing, practised by a significant proportion of women globally, is associated with acquisition of human immunodeficiency virus (HIV), sexually transmitted infections and bacterial vaginosis (BV). ...