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The role of cytotoxic T-cells in HIV infection
(University of Nairobi, 1998)
HIV-specific cytotoxic T lymphocytes (CTL) are believed to play a major role in controlling virus levels through the asymptomatic period of HIV infection. For the rational design of an HIV vaccine, we need to know whether ...
Treatment of Chacroid with a 5-day Low Dose Erythromycin Regimen.
(University of Nairobi, 1992-07)
Low dose erythromycin regimen for the treatment of chancroid
(1995)
Haemophilus ducreyi is the commonest cause of genital ulcer disease in Africa and is associated with heterosexual transmission of human immunodeficiency virus(HIV). The World Health Organization currently recommends ...
Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya
(1996)
BACKGROUND:
There is indirect evidence that HIV-1 exposure does not inevitably lead to persistent infection. Heterogeneity in susceptibility to infection could be due to protective immunity. The objective of this study ...
Comparison of the declines in CD4 counts in HIV-1-seropositive female sex workers and women from the general population in Nairobi, Kenya
(1995)
Studies from Kenya have reported rapid clinical disease progression among HIV-infected professional sex workers. The reasons for this rapid decline are unknown. To better understand factors influencing the course of disease, ...
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
(University of Nairobi, 1998-11)
Many people who remain persistently seronegative despite frequent HIV exposure have HIV-specific immune responses. The study of these may provide information about mechanisms of natural protective immunity to HIV-1. We ...
Association of Chlamydia trachomatis Heat-Shock Protein 60 Antibody and HLA Class II DQ Alleles
(1999)
A total of 113 female commercial sex workers had individual alleles for HLA class II genes determined by using labeled sequence-specific oligonucleotide probes to hybridize to polymerase chain reaction products of amplified ...
Genetic diversity and mosaicism at the por locus of Neisseria gonorrhoeae.
(1999)
The por genes of the predominant serovars of Neisseria gonorrhoeae circulating in a high-frequency transmitter core group located in Nairobi, Kenya, were examined for nucleotide sequence polymorphism. The level of por gene ...
Antibody to chlamydial hsp60 predicts an increased risk for chlamydial pelvic inflammatory disease.
(University of Nairobi, 1997)
Abstract
To determine whether serum antibody to Chlamydia trachomatis antigens alters the risk of C. trachomatis pelvic inflammatory disease (PID), 280 female sex workers were prospectively evaluated over a 33-month ...
The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group.
(University of Nairobi, 1996)
Female sex workers in Nairobi were prospectively evaluated for risk factors of incident Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=.007), gonococcal infection (P=.002), human ...