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Should women with HIV-1 infection breastfeed their infants? It depends on the setting.
(University of Nairobi, 2012)
Breastfeeding is the ideal infant food—it provides both optimal nutrition and numerous factors that contribute to infant immunity, growth, cognition, and health. It also enhances maternal–infant bonding and child-spacing ...
Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya.
(University of Nairobi, 2008-07)
Humoral immunity, and specifically immunoglobulin A (IgA) that is directed against human immunodeficiency virus (HIV)-1, may contribute to protection against HIV-1 acquisition at mucosal surfaces. HIV-1-specific IgA has ...
Cofactors for HIV-1 incidence during pregnancy and postpartum period.
(2010-10)
OBJECTIVES:
to estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.
DESIGN:
retrospective study among women who were HIV seronegative during pregnancy.
METHODS:
mothers ...
Clinical and Virologic Manifestations of Primary Epstein-Barr Virus (EBV) Infection in Kenyan Infants Born to HIV-Infected Women.
(University of Nairobi, 2013-06)
Background. Human immunodeficiency virus (HIV) infection is a risk factor for Epstein-Barr virus (EBV)-associated lymphomas. Characterizing primary infection may elucidate risk factors for malignancy. Methods. To describe ...
Short-term effect of zidovudine on plasma and genital human immunodeficiency virus type 1 and viral turnover in these compartments
(University of Nairobi., 2003-07)
The effect of zidovudine on plasma and genital human immunodeficiency virus type 1 (HIV-1) was determined in 42 antiretroviral-naive HIV-1-seropositive women in Nairobi. After 7 days of zidovudine treatment, HIV-1 RNA ...
Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya
(University of Nairobi., 2008-07)
Humoral immunity, and specifically immunoglobulin A (IgA) that is directed against human immunodeficiency virus (HIV)-1, may contribute to protection against HIV-1 acquisition at mucosal surfaces. HIV-1-specific IgA has ...
High maternal HIV-1 viral load during pregnancy is associated with reduced placental transfer of measles IgG antibody.
(University of Nairobi., 2005-12)
BACKGROUND:
Studies among HIV-1-infected women have demonstrated reduced placental transfer of IgG antibodies against measles and other pathogens. As a result, infants born to women with HIV-1 infection may not acquire ...
Prevalence and magnitude of human immunodeficiency virus (HIV) type 1-specific lymphocyte responses in breast milk from HIV-1-seropositive women.
(2003)
Human immunodeficiency virus (HIV) type 1-specific cell-mediated immunity of breast milk may influence the likelihood of mother-to-child transmission of HIV-1 via breast-feeding. In breast-milk specimens collected during ...
Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeeding.
(University of Nairobi., 2007-03)
Previous studies of HIV-1 variants transmitted from mother-to-infant have focused primarily on computational analyses of partial envelope gene sequences, rather than analyses of functional envelope variants. There are very ...
Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant
(University of Nairobi., 2006-01)
Maternal passive immunity typically plays a critical role in protecting infants from new infections; however, the specific contribution of neutralizing antibodies in limiting mother-to-child transmission of human ...