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Disease progression by infecting HIV-1 subtype in a seroconverter cohort in sub-Saharan Africa.
(Universty of Nairobi, 2013-10-09)
OBJECTIVE::
To describe immunologic, virologic, and clinical HIV disease progression by HIV-1 subtype among Africans with well documented estimated dates of HIV infection (EDIs).
DESIGN::
Prospective cohort.
METH ...
Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions
(2014)
Research in the past two decades has generated unequivocal evidence that host genetic variations substantially account for the heterogeneous outcomes following human immunodeficiency virus type 1 (HIV-1) infection. In ...
Dynamics of viremia in primary HIV-1 infection in Africans: Insights from analyses of host and viral correlates.
(University of Nairobi, 2014)
In HIV-1 infection, plasma viral load (VL) has dual implications for pathogenesis and public health. Based on well-known patterns of HIV-1 evolution and immune escape, we hypothesized that VL is an evolving quantitative ...