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Early HIV-1 Infection Is Associated With Reduced Frequencies of Cervical Th17 Cells.
(2015)
BACKGROUND::
The hallmark of HIV infection is progressive but variable rates of systemic and mucosal CD4 depletion, leading to immunodeficiency. The impact of early HIV infection on cervical CD4 T-cell populations in ...
Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility
(2011)
The HIV pandemic disproportionately affects women, with most infections acquired through receptive vaginal sex. Although the target cells by which HIV establishes infection in the female genital tract remain poorly defined, ...
Association of sex work with reduced activation of the mucosal immune system
(University of Nairobi, 2014-01)
Background. Unprotected intercourse and seminal discharge are powerful activators of the mucosal immune system and are an important risk factors for HIV transmission. This study was designed to determine if female sex work ...