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Human immunodeficiency virus infection among men with sexually transmitted diseases. Experience from a center in Africa
(1988)
Heterosexual transmission of the human immunodeficiency virus (HIV) appears to occur readily in Africa but less commonly in North America and Europe. We conducted a case-control study among men attending a clinic for ...
The clinical diagnosis of genital ulcer disease in men in the tropics
(University of Nairobi,, 1984-06)
Since the clinical diagnosis of genital ulcers without laboratory confirmation is not reliable in developed countries, we postulated that clinical diagnosis alone would be no more reliable in developing countries. A ...
Short-course and single-dose antimicrobial therapy for chancroid in Kenya: studies with rifampin alone and in combination with trimethoprim.
(University of Nairobi,, 1983-08)
Tetracyclines and sulfonamides are no longer effective for the treatment of chancroid in many parts of the world. Rifampin and trimethoprim both possess in vitro activity against Haemophilus ducreyi, the causative agent ...
Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase-positive Haemophilus ducreyi infection.
(University of Nairobi,, 1982-09)
Multiresistant strains of Haemophilus ducreyi, the aetiological agent of chancroid, are prevalent in Nairobi, Kenya, where tetracyclines and sulphonamides are no longer very effective in the treatment of chancroid. The ...
Single-dose therapy of chancroid with trimethoprim-sulfametrole
(University of Nairobi,, 1983-07)
We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone ...
Three day oral course of Augmentin to treat chancroid.
(1986)
Amoxycillin and clavulanic acid (Augmentin; Beecham Research Laboratories) was used to treat patients with bacteriologically proved chancroid in three different dose regimens. A single dose of Augmentin (amoxycillin 3 g, ...
Cefotaxime treatment of Haemophilus ducreyi infection in Kenya.
(University of Nairobi,, 1984-12)
The authors conducted a double-blind randomized clinical trial comparing single-dose cefotaxime (1 g im) plus daily placebo injections with cefotaxime (1 g im on each of three days). Each regimen was given with probenicid ...
Antimicrobial therapy of chancroid: effectiveness of erythromycin
(University of Nairobi,, 1983-10)
The emergence of Haemophilus ducreyi resistant to multiple antibiotics has limited the effectiveness of sulfonamides and tetracycline for the therapy of chancroid. A randomized, double-blind study compared 10-day courses ...
Clinical and microbiologic studies of genital ulcers in Kenyan women.
(University of Nairobi,, 1985-12)
The etiology of genital ulcers in women in tropical regions is poorly understood. Eighty-nine women, presenting to a sexually transmitted disease clinic in Nairobi (Kenya) with a primary complaint of genital ulcers, were ...
Antimicrobial therapy of chancroid: an evaluation of five treatment regimens correlated with in vitro sensitivity
(University of Nairobi,, 1983-03)
One hundred fifty-one men with genital ulcer disease were assigned randomly to treatment with one of five oral antimicrobial regimens: (1) sulfadimidine (1 g four times daily for seven days); (2) tetracycline (500 mg four ...