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Health-care Providers'perceptions Of Intravaginal Rings For Hiv Prevention In Nairobi, Kenya
(2013)
Background: Health-care providers form the backbone of health information and service delivery in many African communities. This study investigated health-care providers' (HCPs) attitudes towards a novel method of HIV ...
Disease progression by infecting HIV-1 subtype in a seroconverter cohort in sub-Saharan Africa.
(Universty of Nairobi, 2013-10-09)
OBJECTIVE::
To describe immunologic, virologic, and clinical HIV disease progression by HIV-1 subtype among Africans with well documented estimated dates of HIV infection (EDIs).
DESIGN::
Prospective cohort.
METH ...
Phase I Safety and Immunogenicity of Electroporated HIV DNA with or Without Interleukin 12 in Healthy HIVSeronegative African Volunteers
(University of Nairobi, 2013)
Background: DNA vaccines have typically been safe in clinical
trials, but weakly immunogenic. Strategies to enhance their immunogenicity
include i) co-administration of adjuvants and ii)
intramuscular administration by ...
Mucosal specimen collection, processing and assay - Experience from a resource-limited setting in Kenya
(University of Nairobi, 2013)
Background:
HIV-1 infection occurs most commonly through
sexual intercourse. Induction of mucosal immune responses will
likely be necessary for an effective HIV vaccine. KAVI embarked
on building capacity for mucosal ...
Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.
(Universty of Nairobi, 2013-11)
Emergence of SIV and HIV specific CD8 T cells has been shown to correlate with control of in vivo replication. Poor correlation between IFN-γ ELISPOT responses and in vivo control of the virus has triggered the development ...