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Reasons for Change of Anti-Retroviral Therapy (ART) Drugs: Local Experience
(University of Nairobi, 2014)
Background: Highly active anti-retroviral therapy (HAART) reduces morbidity and mortality in HIV/AIDS infected patients. HAART is used indefinitely and the regimens are changed over the course of treatment due to resistance, ...
Pyomyositis in HIV: A Series of 12 Cases
(University of Nairobi, 2014)
Background: Pyomyositis is a bacterial infection of the large skeletal muscles presenting with muscle pain and swelling. It is commonly seen in the tropics but is being recognised more in end-stage HIV/AIDS. In HIV-associated ...
CD4+ Cell Response to Anti-Retroviral Therapy (ARTS) In Routine Clinical Care Over One Oear Oeriod in a Cohort of HAART Naive, HIV Positive Kenyan Patients
(University of Nairobi, 2014)
Background: Untreated HIV/AIDS leads to severe immune depletion with opportunistic
infections and other co-morbidities. Highly active anti-retroviral ...
Diabetes Mellitus/HIV Interphase: A Series of 10 Cases
(University of Nairobi, 2014)
Background: Evidence shows that the use of protease inhibitors (PIs) in HIV/AIDS patients leads to the development of diabetes mellitus. Some degree of insulin resistance has also been noted in HIV infected patients not ...
Cholangiopathy in a Co-Hort of HIV Positive Kenyan Patients
(University of Nairobi, 2014)
Background: AIDS (acquired immunodeficiency syndrome) related cholangiopathy results from the inflammation of biliary tree and gall bladder. It is an uncommon manifestation of advanced HIV/AIDS that was associated with ...
Morbidity and CD4+ Cell Counts at Initial Presentation of a Cohort of HAART-Naive, HIV Positive Kenyan Patients: Implications to Initiating HAART
(University of Nairobi, 2014)
Background: Sub-Saharan Africa with under 10% of the worldfs total population accounts for 60-70% of all HIV/AIDS cases. While these patients require HAART to manage the disease, HAART is not universally available. Majority ...
Anti-Retroviral Therapy Related Liver Injury A Series of 11 Cases
(University of Nairobi, 2014)
Background: HIV Anti-retroviral therapy (ART) related liver injury (ARLI) is
associated with elevated liver transaminases (AST/ALT), potential liver failure and death. It is commonly associated with nevirapine. Identification ...
Occurrence of crystal arthropathy in patients presenting with synovitis in Nairobi
(2014)
Background: Crystal arthropathies represent a heterogeneous group of skeletal (musculo-skeletal) diseases associated with the deposition of mineralized material within joints and periarticular soft tissues. Gout is the ...