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Correlates of age at attainment of developmental milestones in HIV-infected infants receiving early antiretroviral therapy
(University of Nairobi, 2015)
Background: Infant HIV-1 infection is associated with impaired neurologic and motor development. Antiretroviral therapy (ART) has the potential to improve developmental outcomes but the relative contributions of pre-ART ...
Home-based HIV testing for men preferred over clinic-based testing by pregnant women and their male partners, a nested cross-sectional study
(University of Nairobi, 2015)
Background
Male partner HIV testing and counseling (HTC) is associated with enhanced uptake of prevention of mother-to-child HIV transmission (PMTCT), yet male HTC during pregnancy remains low. Identifying settings ...
Passively acquired antibody-dependent cellular cytotoxicity (adcc) activity in hiv-infected infants is associated with reduced mortality
(University of Nairobi, 2015)
In addition to direct effects on virus infectivity, antibodies mediate antibody-dependent cellular cytotoxicity (ADCC), the killing of an antibody-coated virus-infected cell by cytotoxic effector cells. Although ADCC has ...
Changes in the contribution of genital tract infections to HIV acquisition among Kenyan high-risk women from 1993 to 2012
(University of Nairobi, 2015)
Objective: The objective of this study was to understand temporal trends in the contribution of different genital tract infections to HIV incidence over 20 years of follow-up in a cohort of high-risk women.
Design: A ...